China Factory Direct
|
|
| CAS number | 107202-39-1 |
| Product name | N-BOC-L-CYCLOHEXYLGLYCINOL |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Industry | Chiral intermediate for synthesizing drug molecules containing the cyclohexylglycine motif (e.g., protease inhibitors, antimicrobial peptide mimetics) | Deprotection under basic conditions (e.g., NaOH, K2CO3) in inert solvents (e.g., THF, DCM) or acid-catalyzed BOC deprotection (e.g., TFA, HCl), followed by coupling reactions |
| Peptide Synthesis | Non-natural amino acid monomer for introducing a cyclohexyl side chain into solid-phase peptide synthesis (SPPS) to enhance lipophilicity and conformational stability | Used as an Fmoc/BOC doubly protected amino acid; coupled to the peptide chain using coupling reagents (e.g., HBTU/DIPEA), with subsequent BOC deprotection via acidolysis |
| Organic Synthesis | Building block for constructing chiral β-substituted α-amino acid derivatives, applied in asymmetric catalysis and heterocycle synthesis | Participates in transformations such as palladium-catalyzed cross-coupling, olefin metathesis, or cycloadditions; the BOC group provides site-selective protection to facilitate subsequent functionalization |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reverse-phase HPLC with UV detection at 210 nm based on peak area comparison against reference standard. |
| Chiral Purity | Chiral HPLC | Measures enantiomeric excess by separating L- and D-enantiomers on a chiral stationary phase with UV detection. |
| Water Content | Karl Fischer Titration | Determines water content via coulometric or volumetric titration using iodine-based redox reaction. |
| Residual Solvents | GC-FID | Identifies and quantifies residual solvents (e.g., THF, toluene, methanol) using gas chromatography with flame ionization detection. |
| Heavy Metals | ICP-OES | Quantifies total heavy metals (e.g., Pb, Cd, Ni, Fe) after acid digestion by measuring elemental emission spectra. |
| Chloride Impurity | Ion Chromatography | Separates and quantifies chloride ions using suppressed conductivity detection after anion exchange separation. |
| Sulfated Ash | Gravimetric Analysis | Measures inorganic residue after high-temperature combustion in presence of sulfuric acid, reported as weight percent. |
| Appearance | Visual Inspection | Assesses physical state, color, and clarity of solid sample against established visual standards under controlled lighting. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range at which solid transitions to liquid using calibrated capillary method per USP <741>. |
| Particle Size Distribution | Laser Diffraction | Measures particle size distribution by analyzing angular scattering pattern of laser light passed through dispersed sample. |
| pH of Aqueous Solution | Potentiometric pH Measurement | Measures hydrogen ion activity in a saturated aqueous suspension using calibrated pH electrode and meter. |
| Related Substances | HPLC-UV | Detects and quantifies structurally related impurities (e.g., deprotected amine, hydrolysis products) using gradient HPLC with UV detection. |
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 148–152°C |
| Optical Rotation | -14° to -12° (c=1, in methanol) |
| Heavy Metals | <=20 ppm |
|
|
|
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.