China Factory Direct
|
|
| CAS number | 1072945-00-6 |
| Product name | 2,6-DIFLUORO-3-(4,4,5,5-TETRAMETHYL-[1,3,2]-DIOXABOROLAN-2-YL)PYRIDINE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Used as a key intermediate in synthesizing fluorinated pyridine-based drug molecules, including kinase inhibitors and anticancer or antiviral candidates | Suzuki-Miyaura cross-coupling with aryl or heteroaryl halides to construct C–C bonds |
| Agrochemicals | Employed as a structural building block in developing novel fluorinated agrochemicals (e.g., herbicides and insecticides) | Palladium-catalyzed cross-coupling to incorporate the 2,6-difluoropyridine scaffold, enhancing biological activity and metabolic stability |
| Materials Science | Functional building block for synthesizing organic optoelectronic materials (e.g., OLED emissive layers or electron-transport materials) | Suzuki coupling to construct conjugated π-systems, enabling tuning of electronic properties and thermal stability |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reversed-phase HPLC with UV detection at 254 nm, comparing peak area to a certified reference standard. |
| Related Substances | HPLC-UV | Detects and quantifies impurities (e.g., residual starting materials, hydrolysis products) via gradient HPLC-UV against qualified impurity standards or threshold-based reporting. |
| Residual Solvents | GC-FID | Measures trace organic solvents (e.g., THF, toluene, methanol) using gas chromatography with flame ionization detection and internal standard calibration. |
| Water Content | Karl Fischer Titration | Determines water by coulometric or volumetric titration where iodine reacts stoichiometrically with water in a pyridine-free reagent system. |
| Heavy Metals | ICP-MS | Quantifies elemental impurities (e.g., Pd, Ni, Fe) after acid digestion using inductively coupled plasma mass spectrometry with isotope dilution or external calibration. |
| Residual Palladium | ICP-OES | Measures palladium from catalytic residues post-digestion via inductively coupled plasma optical emission spectroscopy at characteristic emission wavelengths. |
| Chloride Content | Ion Chromatography | Separates and quantifies chloride ions using anion-exchange column with suppressed conductivity detection and external calibration. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range at which solid transitions to liquid using controlled heating and visual observation of phase change. |
| Appearance | Visual Inspection | Assesses physical state, color, and presence of foreign particles under controlled white light against defined acceptance criteria. |
| Loss on Drying | Gravimetric Analysis | Measures volatile content by weight loss after drying under specified temperature, vacuum, and time conditions. |
| Specific Optical Rotation | Polarimetry | Determines chiral purity by measuring the angle of rotation of plane-polarized light passing through a solution of known concentration and path length. |
| Particle Size Distribution | Laser Diffraction | Measures particle size distribution in suspension using angular scattering intensity patterns of laser light and Mie theory calculation. |
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline solid |
| Purity | >=98.0% (by GC-MS) |
| Total Impurities | <=2.0% (by GC-MS) |
| Single Impurity | <=0.5% (by GC-MS) |
| Water Content (KF) | <=0.5% |
| Melting Point | 78–82°C |
| Identification (NMR) | Conforms to reference standard |
| Residue on Ignition | <=0.1% |
|
|
|
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.