Methyl 4-Bromo-3-(Trifluoromethyl)benzoate Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 107317-58-8 |
| Product name | Methyl 4-Bromo-3-(Trifluoromethyl)benzoate |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for Methyl 4-Bromo-3-(Trifluoromethyl)benzoate
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk Methyl 4-Bromo-3-(Trifluoromethyl)benzoate Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of Methyl 4-Bromo-3-(Trifluoromethyl)benzoate
| Industry | Application | Process |
|---|---|---|
| Pesticides | Key intermediate for synthesizing pyrethroid insecticides (e.g., cyfluthrin, flumethrin) | Constructs the aromatic ring structure of pyrethroids via organic synthesis steps including nucleophilic substitution, coupling reactions, or reduction |
| Pharmaceuticals | Intermediate for synthesizing bioactive aromatic compounds containing a trifluoromethyl group | Participates in Suzuki coupling, ester hydrolysis, and amidation to build candidate drug molecule scaffolds |
| Fine Chemicals | Aromatic ester building block bearing both bromo and trifluoromethyl functional groups, used in synthesizing functional materials or high-value chemicals | Undergoes metal-catalyzed cross-coupling (e.g., palladium-catalyzed) via its bromo substituent to introduce complex functional groups |
Manufacturing Quality Control of Methyl 4-Bromo-3-(Trifluoromethyl)benzoate
| Test Item | Common Testing Method | Method Overview |
|---|---|---|
| Purity (Active Ingredient Content) | High-Performance Liquid Chromatography (HPLC) | Using a C18 reversed-phase column with acetonitrile-water or methanol-water as the mobile phase, and UV detection at 254 nm. The content of the main component is quantified by external or internal standard method to evaluate purity. |
| Structural Confirmation | Nuclear Magnetic Resonance Spectroscopy (¹H NMR, ¹³C NMR) | Analyze chemical shifts, coupling constants, and integration ratios in proton and carbon spectra to confirm structural features such as benzene ring, ester group, bromine atom, and trifluoromethyl group, verifying the target compound's structure. |
| Bromine Content | Combustion Ion Chromatography (CIC) or ICP-MS | The sample is combusted in an oxygen bomb or digested via microwave digestion. Bromide ion concentration is measured using ion chromatography, or total bromine content is determined directly by Inductively Coupled Plasma Mass Spectrometry (ICP-MS), ensuring compliance with theoretical values. |
| Trifluoromethyl (-CF₃) Verification | Fluorine Elemental Analysis (F-Ion Selective Electrode or IC) | After alkali fusion or oxygen bomb combustion, fluoride ions are released from the sample and quantified using a fluoride ion-selective electrode or ion chromatography to verify the presence and content level of the -CF₃ group. |
| Residual Solvents | Gas Chromatography (GC) | Headspace or direct injection is used; capillary column separates common organic solvents such as methanol, acetonitrile, and DMF, with FID detection for quantification. Results must meet ICH Q3C guidelines for residual solvent limits. |
| Moisture Content | Karl Fischer Titration | Measures trace water content based on the quantitative reaction of iodine, sulfur dioxide, pyridine, and methanol with water, using electrochemical titration. Ensures moisture content is below specified limits (e.g., ≤0.5%). |
| Melting Point | Melting Point Apparatus | Determine the melting range using a digital melting point apparatus and compare with literature values (approximately 78–82°C) to preliminarily assess purity and crystal form consistency. |
| Appearance and Color | Visual Inspection + Color Measurement | Observe the sample as white to off-white crystalline powder. A colorimeter may be used to measure yellowness index (YI) when necessary, ensuring no visible discoloration due to impurities. |
| Heavy Metal Residues | ICP-MS or Atomic Absorption Spectroscopy (AAS) | After sample digestion, determine levels of heavy metals such as lead, cadmium, mercury, and arsenic to ensure compliance with pharmaceutical or agrochemical grade standards (e.g., ≤10 ppm). |
| Inorganic Impurities (e.g., Chlorides, Sulfates) | Colorimetry or Ion Chromatography | Following hydrolysis or dissolution of the sample, add reagents such as silver nitrate or barium chloride. Detect Cl⁻, SO₄²⁻ and other inorganic anions by colorimetric methods or ion chromatography to control process-related impurities. |
Technical Specifications of Methyl 4-Bromo-3-(Trifluoromethyl)benzoate
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 78–82°C |
| Identification (NMR) | Conforms to reference spectrum |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of Methyl 4-Bromo-3-(Trifluoromethyl)benzoate
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of Methyl 4-Bromo-3-(Trifluoromethyl)benzoate
Safety Information of Methyl 4-Bromo-3-(Trifluoromethyl)benzoate
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of Methyl 4-Bromo-3-(Trifluoromethyl)benzoate
Industrial Methyl 4-Bromo-3-(Trifluoromethyl)benzoate Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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