2,4-Bis(trifluoromethyl)benzeneboronic acid pinacol ester Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 1073353-65-7 |
| Product name | 2,4-Bis(trifluoromethyl)benzeneboronic acid pinacol ester |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 2,4-Bis(trifluoromethyl)benzeneboronic acid pinacol ester
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 2,4-Bis(trifluoromethyl)benzeneboronic acid pinacol ester Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 2,4-Bis(trifluoromethyl)benzeneboronic acid pinacol ester
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Key boronate intermediate for synthesizing targeted small-molecule drugs containing trifluoromethyl groups (e.g., kinase inhibitors, GPCR modulators) | Suzuki-Miyaura cross-coupling reaction—couples with aryl/heteroaryl halides under palladium catalysis (e.g., Pd(dppf)Cl₂, Pd(PPh₃)₄) to form C–C bonds |
| Materials Science | Trifluoromethylated conjugated molecular building block for high-performance hole-transport or emissive layers in organic light-emitting diodes (OLEDs) and organic photovoltaics (OPVs) | Palladium-catalyzed C–H activation/directed borylation followed by downstream transformation, or Suzuki coupling with brominated carbazole or diphenylamine derivatives—to introduce strongly electron-withdrawing trifluoromethyl groups for energy-level tuning and carrier mobility control |
| Agrochemical R&D | Building block for novel fluorinated agrochemical active molecules (e.g., fungicidal and insecticidal lead compounds) with enhanced metabolic stability and membrane permeability | Suzuki coupling under mild basic conditions (K₃PO₄, dioxane/H₂O, 80–100 °C) to incorporate the 2,4-bis(trifluoromethyl)phenyl moiety—improving lipophilicity and target-binding selectivity |
Manufacturing Quality Control of 2,4-Bis(trifluoromethyl)benzeneboronic acid pinacol ester
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reverse-phase HPLC with UV detection at 254 nm, based on peak area comparison against reference standard. |
| Related Substances | HPLC-UV | Detects and quantifies impurities (e.g., residual boronic acid, hydrolysis products) by gradient HPLC with UV detection. |
| Residual Solvents | GC-FID | Measures volatile organic solvents (e.g., THF, toluene, methanol) using gas chromatography with flame ionization detection. |
| Water Content | Karl Fischer Titration | Determines water content via coulometric or volumetric titration using iodine-based redox reaction in anhydrous methanol/pyridine medium. |
| Heavy Metals | ICP-MS | Quantifies trace heavy metals (Pb, Cd, Hg, As, Ni) after acid digestion using inductively coupled plasma mass spectrometry. |
| Residual Palladium | ICP-MS | Specifically measures palladium from catalytic synthesis residues using ICP-MS after microwave-assisted acid digestion. |
| Chloride Content | Ion Chromatography | Separates and quantifies chloride ions using suppressed conductivity detection after aqueous extraction. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range of solid-to-liquid transition using calibrated capillary apparatus per USP <741>. |
| Appearance | Visual Inspection | Assesses physical state, color, and presence of foreign particles under controlled white light against defined standards. |
| Loss on Drying | Gravimetric Analysis | Measures weight loss after drying under vacuum at 60 C for 2 hours, indicating volatile and moisture content. |
| Residue on Ignition | Sulfated Ash Test | Determines inorganic residue after high-temperature (700–800 C) incineration following sulfuric acid treatment. |
| Particle Size Distribution | Laser Diffraction | Measures particle size distribution in dry powder form using Mie theory-based light scattering analysis. |
Technical Specifications of 2,4-Bis(trifluoromethyl)benzeneboronic acid pinacol ester
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 112–116°C |
| Identification (NMR) | Consistent with structure |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 2,4-Bis(trifluoromethyl)benzeneboronic acid pinacol ester
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 2,4-Bis(trifluoromethyl)benzeneboronic acid pinacol ester
Safety Information of 2,4-Bis(trifluoromethyl)benzeneboronic acid pinacol ester
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 2,4-Bis(trifluoromethyl)benzeneboronic acid pinacol ester
Industrial 2,4-Bis(trifluoromethyl)benzeneboronic acid pinacol ester Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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