2-AMINO-5-CHLOROPHENYLBORONIC ACID, PINACOL ESTER Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 1073371-77-3 |
| Product name | 2-AMINO-5-CHLOROPHENYLBORONIC ACID, PINACOL ESTER |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Reagent GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 2-AMINO-5-CHLOROPHENYLBORONIC ACID, PINACOL ESTER
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 2-AMINO-5-CHLOROPHENYLBORONIC ACID, PINACOL ESTER Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 2-AMINO-5-CHLOROPHENYLBORONIC ACID, PINACOL ESTER
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Synthesis of pharmaceutical intermediates for constructing aminochloro-substituted biphenyl structures | Used in Suzuki-Miyaura coupling reactions |
| Organic Synthesis | Preparation of complex organic molecules and functional materials via introduction of amino and chloro functional groups | Applied in cross-coupling reactions |
| Chemical Reagents | Employed as boronate ester reagents for modification and synthesis of aromatic compounds | Utilized in catalytic coupling reactions |
Manufacturing Quality Control of 2-AMINO-5-CHLOROPHENYLBORONIC ACID, PINACOL ESTER
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reversed-phase HPLC with UV detection at ~254 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-UV or UPLC-MS | Separation and detection of structurally related impurities (e.g., residual starting materials, dehalogenated/by-product species) using gradient elution and UV or mass-selective detection. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection to quantify volatile organic solvents (e.g., THF, toluene, ethyl acetate) per ICH Q3C guidelines. |
| Heavy Metals (Pb, Cd, Hg, As) | ICP-MS | Multi-element quantification of toxic elemental impurities by inductively coupled plasma mass spectrometry after acid digestion and dilution. |
| Water Content | Karl Fischer Titration (Coulometric) | Electrochemical titration measuring water via iodine generation and stoichiometric reaction with water in anhydrous methanol-based medium. |
| Residue on Ignition | Gravimetric Analysis | Determination of inorganic ash content by high-temperature incineration (~750 °C) followed by precise weighing of residual inorganic matter. |
| Chloride Content | Ion Chromatography (IC) or Potentiometric Titration | Quantification of ionic chloride (e.g., from hydrolysis or salt impurities) via suppressed conductivity detection or silver nitrate titration with endpoint detection. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition measurement using calibrated capillary apparatus; indicative of crystallinity and presence of low-melting impurities. |
| Specific Optical Rotation | [α]D (Polarimetry) | Measurement of chiral purity (if applicable) or identity confirmation using sodium D-line light through a solution in specified solvent and concentration. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry or wet dispersed sample to determine D10, D50, D90 values based on light scattering intensity vs. angle. |
| Bulk and Tapped Density | ASTM D6393 (Tap Density Tester) | Determination of powder flowability and compaction behavior via standardized mechanical tapping and volumetric measurement. |
| Microbial Limits | Membrane Filtration + Culture | Enumeration of aerobic microorganisms and absence testing for specified pathogens (e.g., E. coli, S. aureus) per USP <61>/<62>. |
Technical Specifications of 2-AMINO-5-CHLOROPHENYLBORONIC ACID, PINACOL ESTER
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline solid |
| Purity | >=98.0% (by GC-MS) |
| Total Impurities | <=2.0% (by GC-MS) |
| Single Impurity | <=0.5% (by GC-MS) |
| Water Content (KF) | <=0.5% |
| Melting Point | 142–146°C |
| Identification (NMR) | Consistent with structure |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 2-AMINO-5-CHLOROPHENYLBORONIC ACID, PINACOL ESTER
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 2-AMINO-5-CHLOROPHENYLBORONIC ACID, PINACOL ESTER
Safety Information of 2-AMINO-5-CHLOROPHENYLBORONIC ACID, PINACOL ESTER
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 2-AMINO-5-CHLOROPHENYLBORONIC ACID, PINACOL ESTER
Industrial 2-AMINO-5-CHLOROPHENYLBORONIC ACID, PINACOL ESTER Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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