4-fluoro-2-Methoxy-5-nitroaniline Bulk Supply for Industrial Use

China Factory Direct
CAS number 1075705-01-9
Product name 4-fluoro-2-Methoxy-5-nitroaniline
Stock Stock readily available; annual supply capacity exceeding 1,000 tons.
Grade Agricultural GradeMaterial GradeSpecialty GradeIndustrial Grade
Packaging 25KG/bag500KG/bag1000KG/bag
Sample Test Samples Available (Click to Request Samples)
COA View COA
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Supply Type Bulk / Contract manufacturing / OEM
Shipping FCL / LCL available
Payment Terms Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C).
Manufacturer Greenrock Chemical(China Factory)
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Documents We Provide for 4-fluoro-2-Methoxy-5-nitroaniline

COA TDS SDS NMR MOA Certificate of Origin Transport Report TSCA Declaration Production Flow Chart
Pre-sale: Only COA, SDS and NMR are available.
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 4-fluoro-2-Methoxy-5-nitroaniline Supplier from China

17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.

Industrial Applications of 4-fluoro-2-Methoxy-5-nitroaniline

Industry Application Process
Pharmaceuticals Intermediate for synthesizing antitumor or antibacterial agents Organic synthesis, multistep reactions
Pesticides Active ingredient in fluorinated pesticide formulations Nitration, fluorination, methoxylation
Dyes Intermediate for synthesizing fluorinated azo dyes Diazotization, coupling reactions
Materials Science Monomer or modifier for fluorinated polymer synthesis Polymerization, functionalization

Manufacturing Quality Control of 4-fluoro-2-Methoxy-5-nitroaniline

Test Item Common Testing Methods Method Overview
Appearance and Physical Properties Visual Inspection, Melting Point Determination Observe sample color, crystal form, presence of impurities or particulates; determine melting point range (literature value approximately 120–125 °C) to assess purity.
Content Assay (Main Component Purity) High-Performance Liquid Chromatography (HPLC) Use C18 column with acetonitrile-water (containing 0.1% formic acid) as mobile phase, UV detector (254 nm or 280 nm), external standard method for quantification, capable of separating and quantifying the main component and major impurities.
Related Substances (Impurity Profile) HPLC or UPLC Employ gradient elution program to detect potential impurities such as unreacted starting materials (e.g., fluoronitrobenzene, methoxyaniline derivatives), oxidation products, reduction products, etc., with impurity levels calculated as a percentage of the main component peak area.
Water Content Karl Fischer Titration Utilize the specific reaction between iodine, sulfur dioxide, pyridine, and methanol; measure trace water using potentiometric or coulometric Karl Fischer titration, meeting pharmacopoeial requirements (typically ≤0.5%).
Solvent Residuals Gas Chromatography (GC) Use headspace or direct injection with DB-624 or HP-INNOWAX column and FID detector to detect residual organic solvents such as ethanol, ethyl acetate, DMF, dichloromethane, conforming to ICH Q3C guidelines.
Fluorine Content Ion Selective Electrode (ISE) or Ion Chromatography Convert fluorine in samples to fluoride ions via alkaline fusion or oxygen bomb combustion, then quantify using fluoride ion selective electrode or ion chromatography to ensure fluorine content matches theoretical value (theoretical F content ≈10.9%).
Nitro Group Confirmation Fourier Transform Infrared Spectroscopy (FT-IR) Confirm the presence of nitro group through characteristic absorption peaks (asymmetric and symmetric stretching vibrations at ~1520 cm⁻¹ and ~1340 cm⁻¹), excluding interference from other nitrogen-containing functional groups.
Structural Elucidation Nuclear Magnetic Resonance Spectroscopy (¹H-NMR, ¹³C-NMR) Measure in DMSO-d₆ or CDCl₃ solvent; confirm substitution pattern on benzene ring (ortho/meta/para positions) based on chemical shifts and coupling constants to verify molecular structure accuracy.
Heavy Metal Content Atomic Absorption Spectroscopy (AAS) or ICP-MS After wet digestion of samples, determine residual heavy metals such as lead, cadmium, mercury, and arsenic, complying with pharmacopoeial limits (e.g., Pb ≤10 ppm).
Solubility and pH (Solution Properties) Solubility Testing, pH Meter Determine solubility in water, ethanol, ethyl acetate, etc.; prepare saturated aqueous solution and measure pH (theoretically weakly basic, pH ≈6–7) to evaluate dissolution behavior during process development.
Particle Size Distribution (if solid powder) Laser Particle Size Analyzer If used as an API, determine particle size parameters such as D10, D50, D90 to ensure flowability and homogeneity meet formulation processing requirements.

Technical Specifications of 4-fluoro-2-Methoxy-5-nitroaniline

Test Item Specification
Appearance Orange solid
Purity >=98.0% (GC-MS)
Melting Point 128–132°C
Total Impurities <=2.0%
Single Impurity <=0.5%
Water Content (KF) <=0.5%
Identification (NMR) Consistent with structure
Heavy Metals <=20 ppm
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com

Download COA of 4-fluoro-2-Methoxy-5-nitroaniline

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NMR Spectra of 4-fluoro-2-Methoxy-5-nitroaniline

Safety Information of 4-fluoro-2-Methoxy-5-nitroaniline

Pictograms
Signal Word Warning
Safety Data Sheet

Packaging of 4-fluoro-2-Methoxy-5-nitroaniline

We have a diverse range of chemicals in stock. Available in Bagged goods (25 kg.),Big bags (500 kg.), Big bags (1000 kg.).

Industrial 4-fluoro-2-Methoxy-5-nitroaniline Procurement FAQ

1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.

2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.

3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.

4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.

5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.

6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.

7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.

8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.

9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.

Industrial
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ISO 9001
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