China Factory Direct
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| CAS number | 108-75-8 |
| Product name | 108-75-8 |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty GradeIndustrial GradeElectronic Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Synthesis of pharmaceutical intermediates | Used in the preparation of anticancer and cardiovascular drugs; serves as a basic catalyst or ligand in coupling reactions during organic synthesis |
| Pesticides | Pesticide intermediates | Used to synthesize pyridine-based agrochemicals, including high-efficiency insecticides and herbicides |
| Dyes | Assistant in dye synthesis | Acts as an organic base in dye molecule construction to enhance reaction selectivity and yield |
| Electronics Chemicals | Electronic-grade chemical solvent | Employed as a high-purity polar solvent in semiconductor cleaning or photoresist processes |
| Fine Chemicals | Organic synthesis catalyst | Functions as a mild organic base catalyst in acylation, alkylation, and related reactions |
| Materials Science | Functional material precursor | Used as a ligand in the preparation of nitrogen-containing heterocyclic polymers or metal–organic frameworks (MOFs) |
| Test Item | Common Testing Method | Method Overview |
|---|---|---|
| Purity (Main Component Content) | Gas Chromatography (GC) | Using a capillary column (e.g., DB-5 or HP-5) and FID detector, the content of 2,4,6-trimethylpyridine is quantitatively analyzed via internal or external standard methods. This method effectively separates isomers (e.g., 2,3,6-trimethylpyridine), with a detection limit as low as 0.01%. |
| Impurity Analysis (Organic Impurities) | Gas Chromatography-Mass Spectrometry (GC-MS) | Couples a mass spectrometer to GC for qualitative and semi-quantitative analysis of residual solvents, unreacted raw materials, and by-products (e.g., methylation side products). Provides molecular weight and fragment information, suitable for trace impurity identification. |
| Moisture Content | Karl Fischer Titration | Uses coulometric or volumetric Karl Fischer reagents to accurately determine trace moisture levels (typically required ≤0.1%). Applicable for quality control of moisture-sensitive fine chemicals. |
| Appearance and Color | Visual Color Comparison / Spectrophotometry | Observe sample color under white light (should be colorless to pale yellow transparent liquid), or use a spectrophotometer to measure absorbance in the 400–700 nm range. Quantitative evaluation is performed by comparison with platinum-cobalt color standards (Pt-Co scale). |
| Boiling Range | Distillation Method / Boiling Point Apparatus | Determine initial and final boiling points using a precision distillation setup. The theoretical boiling point of 2,4,6-trimethylpyridine is 201–203°C; measured values should fall within ±2°C, used to assess volatile impurities and compositional uniformity. |
| Acid Value / Base Value | Acid-Base Titration | Titrate acidic impurities (e.g., pyridine oxidation products) with standardized sodium hydroxide solution, or titrate basic impurities with hydrochloric acid. Acid value should be ≤0.1 mg KOH/g to ensure chemical stability. |
| Density | Densimeter / Pycnometer Method | Measure density at constant temperature (20°C or 25°C) using a digital densimeter or pycnometer. The density of 2,4,6-trimethylpyridine is approximately 0.91–0.92 g/cm³, used for identity confirmation and purity assessment. |
| Melting Point (for Solid Samples) | Melting Point Apparatus | If the sample solidifies (e.g., after cold storage), determine melting point using capillary tube method or automated melting point instrument. Theoretical melting point is about 10–12°C, useful for detecting high-melting-point impurities. |
| Chloride Ions / Inorganic Impurities | Ion Chromatography (IC) | Dissolve sample in ultrapure water, separate via ion chromatography, and detect Cl⁻, SO₄²⁻, and other inorganic anions using a conductivity detector. Ensures absence of corrosive impurities (typically limited to ≤1 ppm). |
| Content Uniformity (Between Batches) | GC or HPLC Repeatability Verification | Perform parallel testing on multiple batches and calculate RSD (relative standard deviation). RSD should be ≤1.0%, ensuring process stability and batch-to-batch consistency. |
| Test Item | Specification |
|---|---|
| Appearance | Colorless liquid |
| Purity | >=98.5% (GC) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.3% |
| Refractive Index (n20/D) | 1.492–1.496 |
| Relative Density (20°C/25°C) | 0.905–0.912 g/cm³ |
| Odor | Characteristic pyridine-like odor |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.