4-(1H-IMIDAZOL-2-YL)-BENZOIC ACID Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 108035-45-6 |
| Product name | 4-(1H-IMIDAZOL-2-YL)-BENZOIC ACID |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 4-(1H-IMIDAZOL-2-YL)-BENZOIC ACID
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 4-(1H-IMIDAZOL-2-YL)-BENZOIC ACID Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 4-(1H-IMIDAZOL-2-YL)-BENZOIC ACID
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Chemicals | Pharmaceutical Intermediates | Used in the synthesis of novel angiotensin II receptor blockers (e.g., olmesartan medoxomil) and their active metabolites, contributing to the construction of key pharmacophores. |
| Pharmaceutical Chemicals | Biomedical Research | Serves as a ligand or probe molecule for histamine H₃ receptors or imidazoline receptors, applied in receptor binding assays and structure–activity relationship (SAR) studies. |
| Chemical Synthesis | Organic Synthesis Reagent | Leverages its bifunctional character—combining benzoic acid and imidazole moieties—as a ligand in the construction and synthesis of metal–organic frameworks (MOFs) or coordination polymers. |
| Biochemistry | Metalloenzyme Mimicry | Acts as a model ligand to mimic the active-site structures of natural imidazole-containing metalloenzymes, such as peroxidases and superoxide dismutases. |
Manufacturing Quality Control of 4-(1H-IMIDAZOL-2-YL)-BENZOIC ACID
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 254 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC-UV; identification based on retention time matching and threshold limits per ICH Q3A. |
| Residual Solvents | GC-FID | Detection and quantification of volatile organic solvents (e.g., methanol, acetone, DMF) by gas chromatography with flame ionization detection. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to determine trace water content via stoichiometric reaction. |
| Heavy Metals | ICP-MS | Multi-element quantification of toxic metals (Pb, Cd, Hg, As, etc.) after acid digestion, using inductively coupled plasma mass spectrometry. |
| Chloride Impurity | Ion Chromatography | Separation and quantification of chloride ions using suppressed conductivity detection after anion exchange column separation. |
| Sulfated Ash | Gravimetric Analysis | Residue mass measurement after high-temperature incineration (500–600 C) followed by sulfuric acid treatment and drying. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition determination by observing solid-to-liquid phase change in a capillary tube under controlled heating rate. |
| Appearance | Visual Inspection | Assessment of physical state, color, and presence of foreign particles under standardized white light and against specified reference. |
| pH of Aqueous Suspension | pH Meter | Measurement of pH in a defined suspension (e.g., 1% w/v in water) using calibrated pH electrode after equilibration. |
| Loss on Drying | Thermogravimetric Analysis | Mass loss determination upon heating under controlled temperature and airflow to remove volatile components. |
| Particle Size Distribution | Laser Diffraction | Analysis of particle size distribution in dispersed sample using Mie scattering theory and laser diffraction instrumentation. |
Technical Specifications of 4-(1H-IMIDAZOL-2-YL)-BENZOIC ACID
| Test Item | Specification |
|---|---|
| Appearance | Yellow solid |
| Purity | >=98.0% (HPLC) |
| Melting Point | 245–249 °C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 4-(1H-IMIDAZOL-2-YL)-BENZOIC ACID
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 4-(1H-IMIDAZOL-2-YL)-BENZOIC ACID
Safety Information of 4-(1H-IMIDAZOL-2-YL)-BENZOIC ACID
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 4-(1H-IMIDAZOL-2-YL)-BENZOIC ACID
Industrial 4-(1H-IMIDAZOL-2-YL)-BENZOIC ACID Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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