TERT-BUTYL N-[3-(AMINOMETHYL)BENZYL]CARBAMATE Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 108467-99-8 |
| Product name | TERT-BUTYL N-[3-(AMINOMETHYL)BENZYL]CARBAMATE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty Grade |
| Packaging | 25L/drum |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for TERT-BUTYL N-[3-(AMINOMETHYL)BENZYL]CARBAMATE
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk TERT-BUTYL N-[3-(AMINOMETHYL)BENZYL]CARBAMATE Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of TERT-BUTYL N-[3-(AMINOMETHYL)BENZYL]CARBAMATE
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Intermediate for synthesizing active pharmaceutical ingredients (APIs) containing a benzylaminomethyl moiety, such as kinase inhibitors and G protein-coupled receptor modulators | Used as a protected aminomethyl aniline derivative in solid-phase or solution-phase peptide/small-molecule synthesis; after deprotection (TFA treatment), the liberated amine undergoes amidation, ureation, or reductive amination with carboxylic acids, isocyanates, or aldehydes |
| Organic Synthesis | Multifunctional amino-protecting building block enabling site-selective introduction of the —CH₂NH₂ group | After palladium-catalyzed cross-coupling (e.g., Suzuki, Heck) to modify the aryl ring, the Boc protecting group is selectively removed under acidic conditions (e.g., trifluoroacetic acid) to liberate the primary amine for subsequent functionalization |
| Agrochemical R&D | Potential nitrogen-containing heterocyclic precursor for constructing bioactive benzylamine-based insecticidal or fungicidal scaffolds | Participates in cyclization reactions (e.g., condensation with CS₂ or halo-carbonyl compounds) to form heterocyclic cores such as thiadiazoles, triazoles, or pyrimidines; the Boc group prevents undesired side reactions involving the amino group during these transformations |
Manufacturing Quality Control of TERT-BUTYL N-[3-(AMINOMETHYL)BENZYL]CARBAMATE
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 210-220 nm, comparing peak area to a certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC-UV; identification based on retention time matching and threshold limits per ICH Q3A/B. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify common solvents (e.g., methanol, ethyl acetate, toluene) against calibrated standards. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to determine trace water via stoichiometric reaction. |
| Heavy Metals | ICP-MS | Multi-element detection of Pb, Cd, Hg, As, and others at sub-ppb levels after acid digestion and matrix-matched calibration. |
| Chloride Content | Ion Chromatography | Separation and quantification of chloride anion using suppressed conductivity detection with sodium carbonate/bicarbonate eluent. |
| Residual Palladium | ICP-OES | Quantification of Pd after microwave-assisted acid digestion, using characteristic emission lines and internal standard correction. |
| Optical Rotation | [alpha]D Measurement | Determination of specific rotation using a digital polarimeter at 20 C and 589 nm (Na D-line) in specified solvent and concentration. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition observed visually or automatically as the temperature range over which solid-to-liquid phase change occurs. |
| Appearance | Visual Inspection | Assessment under controlled white light against defined standards for color, clarity, and physical form (e.g., white to off-white crystalline powder). |
| Particle Size Distribution | Laser Diffraction | Analysis of dry or dispersed sample using Mie theory to derive volume-based particle size distribution from scattered laser light. |
| Microbial Limits | Membrane Filtration | Enumeration of aerobic mesophilic bacteria and fungi following filtration, membrane transfer to selective agar media, and incubation per USP <61>. |
Technical Specifications of TERT-BUTYL N-[3-(AMINOMETHYL)BENZYL]CARBAMATE
| Test Item | Specification |
|---|---|
| Appearance | Colorless liquid |
| Purity | >=98.0% (HPLC) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Odor | Characteristic, mild |
| Solubility | Soluble in common organic solvents (e.g., dichloromethane, methanol, ethyl acetate) |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of TERT-BUTYL N-[3-(AMINOMETHYL)BENZYL]CARBAMATE
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of TERT-BUTYL N-[3-(AMINOMETHYL)BENZYL]CARBAMATE
Safety Information of TERT-BUTYL N-[3-(AMINOMETHYL)BENZYL]CARBAMATE
| Pictograms |  |
| Signal Word | Danger |
| Safety Data Sheet | |
Packaging of TERT-BUTYL N-[3-(AMINOMETHYL)BENZYL]CARBAMATE
Industrial TERT-BUTYL N-[3-(AMINOMETHYL)BENZYL]CARBAMATE Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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