H-GLU(OTBU)-NH2 HCL Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 108607-02-9 |
| Product name | H-GLU(OTBU)-NH2 HCL |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for H-GLU(OTBU)-NH2 HCL
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk H-GLU(OTBU)-NH2 HCL Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of H-GLU(OTBU)-NH2 HCL
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Used as a chiral intermediate in the synthesis of glutaminase inhibitors or antitumor agents | Multi-step organic synthesis involving amino group protection and deprotection, condensation, and chiral resolution |
| Pharmaceuticals | Used to prepare peptide compounds containing the γ-glutamyl moiety | Solid-phase or liquid-phase peptide synthesis (SPPS/LPPS), commonly introduced as a side-chain modification unit |
| Biochemical Research | Used as a tool molecule to study enzyme activity related to glutamine metabolism | Employed as a substrate analog or inhibitor precursor in enzyme kinetic assays |
Manufacturing Quality Control of H-GLU(OTBU)-NH2 HCL
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reversed-phase HPLC with UV detection at ~210 nm, comparing peak area against a certified reference standard. |
| Enantiomeric Purity | Chiral HPLC | Separation and quantification of (S)- and (R)-enantiomers using a chiral stationary phase; enantiomeric excess calculated from peak areas. |
| Residual Solvents (e.g., tert-butanol, DCM, MeOH) | GC-FID | Headspace or direct injection GC with flame ionization detection, quantifying volatile organic solvents against calibrated standards. |
| Water Content | Karl Fischer Titration (Coulometric) | Electrochemical titration based on the stoichiometric reaction of iodine with water in anhydrous pyridine/methanol medium. |
| Heavy Metals (Pb, Cd, Hg, As) | ICP-MS | Multi-element quantification via plasma ionization and mass spectrometric detection, achieving sub-ppt sensitivity per USP <232>/<233>. |
| Residual Chloride (Cl⁻) | Ion Chromatography (IC) with Conductivity Detection | Anion separation on a high-capacity column followed by suppressed conductivity detection; quantified against chloride standard calibration. |
| Residual tert-Butyl Carbonate (Boc-anhydride derivative impurity) | HPLC-UV | Specific detection and quantification of Boc-related degradation products using gradient RP-HPLC and UV absorbance. |
| Acid Value (Free HCl content) | Acid-Base Potentiometric Titration | Titration with standardized NaOH solution using pH electrode endpoint detection to quantify protonated amine hydrochloride and free acid equivalents. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry powder dispersion via Mie scattering theory to determine D10, D50, D90 values per ISO 13320. |
| Microbial Contamination (Bioburden) | Membrane Filtration + TSA/SDA Culture | Quantitative enumeration of aerobic bacteria and fungi after filtration and incubation on tryptic soy agar/sabouraud dextrose agar per USP <61>. |
Technical Specifications of H-GLU(OTBU)-NH2 HCL
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.0% (HPLC) |
| Optical Rotation | +17.5 to +18.5° (c=1, in 1M HCl) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% (HPLC) |
| Single Impurity | <=0.5% (HPLC) |
| Melting Point | 148 to 152°C |
| Identification (NMR) | Conforms to reference spectrum |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of H-GLU(OTBU)-NH2 HCL
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of H-GLU(OTBU)-NH2 HCL
Packaging of H-GLU(OTBU)-NH2 HCL
Industrial H-GLU(OTBU)-NH2 HCL Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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