China Factory Direct
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| CAS number | 108966-71-8 |
| Product name | 3,4-DIFLUOROBENZENESULFONAMIDE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Antimicrobial drug intermediate for synthesizing fluoroquinolone antibiotics (e.g., sitafloxacin derivatives) | Produced via ammonolysis with 3,4-difluorobenzenesulfonyl chloride, followed by cyclization and substitution steps to construct the quinolone core structure |
| Agrochemicals | Key intermediate for novel fungicides and insecticides, used in synthesizing fluorinated sulfonamide agrochemical active ingredients | Used as a starting material in condensation reactions with heterocyclic amines to introduce the 3,4-difluorobenzenesulfonamide group, enhancing lipophilicity and target-binding affinity |
| Materials Science | Functionalization unit for organic optoelectronic materials (e.g., hole-transport layers in OLEDs) | Linked to conjugated backbones such as carbazole or triarylamines via Suzuki or Ullmann coupling reactions to tune HOMO energy levels and thin-film morphology |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reversed-phase HPLC with UV detection at 220-254 nm based on peak area comparison against reference standard. |
| Related Substances | HPLC-UV | Detects and quantifies structurally related impurities using gradient HPLC-UV; identification via retention time matching and relative response factors. |
| Residual Solvents | GC-FID | Measures volatile organic solvents (e.g., methanol, acetone, toluene) by gas chromatography with flame ionization detection using headspace sampling. |
| Water Content | Karl Fischer Titration | Determines water by coulometric or volumetric titration with iodine-based reagent; based on stoichiometric reaction of water with iodine and sulfur dioxide. |
| Heavy Metals | ICP-OES | Quantifies Pb, Cd, Hg, As, and other heavy metals after acid digestion using inductively coupled plasma optical emission spectrometry. |
| Chloride Impurity | Ion Chromatography | Separates and quantifies chloride ions using suppressed conductivity detection after aqueous extraction and filtration. |
| Sulfate Impurity | Ion Chromatography | Separates and quantifies sulfate ions using suppressed conductivity detection following sample dissolution and dilution. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range at which solid transitions to liquid using calibrated capillary apparatus per USP <741>. |
| Appearance | Visual Inspection | Assesses physical state, color, and presence of foreign particles under controlled white light against defined standards (e.g., white to off-white crystalline powder). |
| Loss on Drying | Gravimetric Analysis | Measures weight loss after drying at 105 C for 2 hours; reflects volatile content including residual solvents and moisture. |
| Residue on Ignition | Sulfated Ash Test | Determines inorganic residue after controlled charring and ashing at 600-700 C; indicates non-volatile inorganic impurities. |
| Specific Optical Rotation | Polarimetry | Measures rotation of plane-polarized light at 20 C using sodium D-line (589 nm); confirms chiral integrity if applicable (though compound is achiral, test verifies absence of optically active contaminants). |
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.5% (by LC-MS) |
| Melting Point | 124–128 °C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.3% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Danger |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.