3-Hydroxypyridine Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 109-00-2 |
| Product name | 3-Hydroxypyridine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty GradeIndustrial GradeReagent Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 3-Hydroxypyridine
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 3-Hydroxypyridine Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 3-Hydroxypyridine
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate in the synthesis of the antitubercular drug pyrazinamide | Pyrazinamide is produced via diazotization of 3-hydroxypyridine with sodium nitrite under acidic conditions, followed by reduction and cyclization |
| Agrochemicals | Key structural building block for synthesizing novel neonicotinoid insecticides (e.g., imidacloprid derivatives) | Used as a heterocyclic scaffold in N-alkylation, chlorination, and coupling reactions to construct pyridine-containing bioactive molecules |
| Dyes | Intermediate for azo dyes and fluorescent whitening agents | After diazotization, coupled with aromatic amines or phenols to generate azo compounds with specific chromophoric properties |
| Materials Science | Building block for metal–organic framework (MOF) ligands and functionalized polymer monomers | The 3-hydroxy group serves as a coordination site for metal ions (e.g., Zn²⁺, Cu²⁺); alternatively, esterified or etherified derivatives are employed in copolymerization reactions |
| Analytical Chemistry | Reference standard for high-performance liquid chromatography (HPLC) and raw material for pH-sensitive fluorescent probes | Pure compound used directly for calibration; or derivatized (e.g., sulfonation, bromination) for trace metal ion detection |
Manufacturing Quality Control of 3-Hydroxypyridine
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification by comparison of peak area against a certified reference standard using reversed-phase chromatography and UV detection at 254 nm. |
| Appearance | Visual Inspection | Assessment of physical state and color by observation against standard white background under controlled lighting. |
| Melting Point | Capillary Melting Point Determination | Measurement of temperature range at which solid transitions to liquid using calibrated capillary apparatus per USP <741>. |
| Water Content | Karl Fischer Titration | Electrochemical titration with iodine-based reagent to quantify water based on stoichiometric reaction. |
| Residue on Ignition | Gravimetric Analysis | Weighing residue remaining after high-temperature ashing to determine inorganic impurities. |
| Heavy Metals | ICP-OES | Multi-element quantification of toxic metals (e.g., Pb, Cd, Hg) by atomic emission spectroscopy after acid digestion. |
| Chloride Impurity | Ion Chromatography | Separation and quantification of chloride anions using suppressed conductivity detection. |
| Sulfated Ash | Gravimetric Analysis | Determination of non-volatile inorganic residue after ignition with sulfuric acid treatment. |
| Related Substances | HPLC-UV | Identification and quantification of structurally related impurities using gradient elution and UV detection. |
| pH of Aqueous Solution | Potentiometric pH Measurement | Determination of hydrogen ion activity in 1% w/v aqueous solution using calibrated pH electrode. |
| Solubility | Qualitative Solubility Test | Observation of complete dissolution in specified solvents (e.g., water, ethanol, methanol) at 20 C. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation of plane-polarized light to confirm chiral purity and identity (though 3-hydroxypyridine is achiral, this verifies absence of chiral contaminants). |
Technical Specifications of 3-Hydroxypyridine
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow solid |
| Purity | >=98.0% (HPLC) |
| Melting Point | 65-69°C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 3-Hydroxypyridine
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 3-Hydroxypyridine
Packaging of 3-Hydroxypyridine
Industrial 3-Hydroxypyridine Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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