2-(chloromethyl)-4-methylquinazoline Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 109113-72-6 |
| Product name | 2-(chloromethyl)-4-methylquinazoline |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeReagent Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 2-(chloromethyl)-4-methylquinazoline
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 2-(chloromethyl)-4-methylquinazoline Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 2-(chloromethyl)-4-methylquinazoline
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate for synthesizing antitumor and antiviral drugs | Prepared via chloromethylation of quinazoline derivatives; commonly employed in subsequent nucleophilic substitution reactions to construct drug molecule scaffolds |
| Agrochemicals | Intermediate for synthesizing novel fungicides or insecticides | Undergoes alkylation with nitrogen-containing heterocyclic compounds via the chloromethyl group to build active molecular structures |
| Chemical Reagents | Electrophilic reagent in organic synthesis | Used in laboratory-scale reactions with nucleophiles such as amines, alcohols, and thiols to introduce the quinazolinyl group |
Manufacturing Quality Control of 2-(chloromethyl)-4-methylquinazoline
| Test Item | Common Testing Method | Method Description |
|---|---|---|
| Appearance | Visual Inspection | Observe the color and physical state (e.g., white to off-white crystalline powder) of the sample with the naked eye to determine if it meets standard requirements. |
| Identification | Infrared Spectroscopy (IR) | Determine the infrared absorption spectrum of the sample and compare characteristic absorption peaks (e.g., C–Cl, C=N, aromatic rings) with a reference spectrum. |
| Proton Nuclear Magnetic Resonance (¹H NMR) | Confirm the molecular structure by analyzing the chemical shifts and integration ratios of protons in the ¹H NMR spectrum. | |
| Content Determination | High-Performance Liquid Chromatography (HPLC) | Use reversed-phase HPLC with a C18 column for separation. Quantify the main component using a UV detector (e.g., at 254 nm) and calculate the content via external standard method. |
| Related Substances (Impurities) | High-Performance Liquid Chromatography (HPLC) | Use the same conditions as content determination or gradient elution programs to detect and quantify process-related impurities and degradation products. |
| Loss on Drying | Thermogravimetric Analysis / Oven-Drying Method | Dry the sample at a specified temperature (e.g., 105°C) until constant weight is achieved, then calculate the percentage of mass loss to assess moisture and volatile substance content. |
| Residue on Ignition | High-Temperature Ashing Method | Weigh the inorganic residue after heating the sample at high temperatures (e.g., 700–800°C), used to control inorganic impurity levels. |
| Chloride Content | Ion Chromatography (IC) or Potentiometric Titration | Determine the chloride ion content after conversion from organic chlorine, used to evaluate halogen impurity levels (if free chloride ions need to be controlled). |
| Residual Solvents | Gas Chromatography (GC) | Use headspace injection or direct injection GC to detect residual organic solvents (e.g., dichloromethane, ethanol) that may remain from the synthesis process. |
| Melting Point | Capillary Melting Point Determination | Determine the melting temperature range of the sample, serving as an auxiliary indicator for purity and crystal form. |
| pH Value (if dissolved in solution) | pH Meter Measurement | Dissolve the sample in water or an appropriate solvent system to prepare a solution of certain concentration and measure its pH to evaluate the impact of acidic or basic impurities. |
Technical Specifications of 2-(chloromethyl)-4-methylquinazoline
| Test Item | Specification |
|---|---|
| Appearance | Yellow solid |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Melting Point | 148–152 °C |
| Water Content (KF) | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Heavy Metals | <=20 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 2-(chloromethyl)-4-methylquinazoline
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 2-(chloromethyl)-4-methylquinazoline
Safety Information of 2-(chloromethyl)-4-methylquinazoline
| Pictograms |    |
| Signal Word | Danger |
| Safety Data Sheet | |
Packaging of 2-(chloromethyl)-4-methylquinazoline
Industrial 2-(chloromethyl)-4-methylquinazoline Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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