FMOC-D-GLU-OTBU Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 109745-15-5 |
| Product name | FMOC-D-GLU-OTBU |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for FMOC-D-GLU-OTBU
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk FMOC-D-GLU-OTBU Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of FMOC-D-GLU-OTBU
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate for peptide synthesis, used to construct peptide chains containing glutamic acid residues | Fmoc-based protection strategy in solid-phase peptide synthesis (SPPS) |
| Biochemistry | Amino acid protection reagent for preparing research-grade peptide compounds | Liquid-phase synthesis or fragment condensation reactions |
| Pharmaceutical R&D | Functional molecular fragment for synthesizing targeted therapeutics or diagnostic agents | Carboxyl and amino group protection/deprotection operations in organic synthesis |
Manufacturing Quality Control of FMOC-D-GLU-OTBU
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 260–280 nm, comparing peak area against a certified reference standard. |
| Chiral Purity | Chiral HPLC | Separation and quantification of D- vs L-enantiomer using a chiral stationary phase; enantiomeric excess calculated from peak area ratio. |
| Residual Solvents (e.g., DMF, DCM, MTBE) | GC-FID | Headspace or direct injection GC with flame ionization detection, quantifying solvents against calibrated standards per ICH Q3C guidelines. |
| Water Content | Karl Fischer Titration (Coulometric) | Electrochemical titration where iodine is generated in situ to react stoichiometrically with water; endpoint detected amperometrically. |
| Heavy Metals (Pb, Cd, Hg, As) | ICP-MS | Multi-element quantification after acid digestion and dilution, using isotopic detection for sub-ppb sensitivity per ICH Q3D. |
| Residual Chloride | Ion Chromatography (IC) with Conductivity Detection | Separation of chloride anion on an anion-exchange column followed by quantitative conductivity detection against chloride calibration standards. |
| Related Substances (Impurities) | HPLC-UV (Forced Degradation Compatible) | Gradient HPLC-UV method validated for specificity, detecting and quantifying structurally related impurities (e.g., deprotected glutamic acid, Fmoc-Glu-OH, di-tert-butyl ester). |
| Appearance & Color | Visual Inspection / APHA Color Scale | Subjective assessment against water or platinum-cobalt standards under controlled lighting per USP <1092>. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition measurement via controlled heating; onset and range compared to reference material per USP <741>. |
| Residual Palladium (if Pd-catalyzed synthesis used) | ICP-OES | Quantification after microwave-assisted acid digestion using characteristic atomic emission lines; compliant with catalyst residue limits per ICH Q3C/Q3D. |
Technical Specifications of FMOC-D-GLU-OTBU
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% (LC-MS) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Optical Rotation | +9.5 to +10.5° (c=1, DMF) |
| Melting Point | 148 to 152°C |
| Identification (NMR) | Conforms to reference spectrum |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of FMOC-D-GLU-OTBU
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of FMOC-D-GLU-OTBU
Packaging of FMOC-D-GLU-OTBU
Industrial FMOC-D-GLU-OTBU Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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