China Factory Direct
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| CAS number | 110238-91-0 |
| Product name | Methyl tetrahydropyran-4-carboxylate |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Key chiral building block for synthesizing antiviral agents (e.g., HCV NS5A inhibitors) | Constructs the active molecular core via hydrolysis, amidation, and other steps following chiral catalytic hydrogenation or enzymatic resolution |
| Organic Synthesis | Protecting group reagent for selective protection and deprotection of hydroxyl groups | Forms tetrahydropyranyl ethers with alcohol substrates under acid catalysis (e.g., PPTS), followed by mild deprotection under weakly acidic conditions (e.g., PPTS/MeOH) |
| Pesticide Development | Synthetic precursor for nitrogen-containing heterocyclic side chains in novel insecticides | Introduces functionalized tetrahydropyran ring structures via ester hydrolysis, condensation, and cyclization reactions |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | Gas Chromatography (GC) with FID detection | Quantifies main component by retention time and peak area against calibrated standard. |
| Related Substances | High Performance Liquid Chromatography (HPLC) with UV detection | Separates and quantifies impurities based on retention time and UV absorbance. |
| Water Content | Karl Fischer Titration | Measures water via stoichiometric reaction between water and iodine in pyridine/methanol medium. |
| Residue on Ignition | Gravimetric Analysis | Determines inorganic ash content after high-temperature incineration and weighing. |
| Heavy Metals | Atomic Absorption Spectroscopy (AAS) | Quantifies metals (e.g., Pb, Cd, Hg) by atomic absorption of characteristic wavelength light. |
| Chloride Impurity | Ion Chromatography (IC) | Separates and quantifies chloride ions using anion-exchange column and conductivity detection. |
| Acid Value | Acid-Base Titration with NaOH | Measures free carboxylic acid groups by titration with standardized sodium hydroxide solution. |
| Specific Optical Rotation | Polarimetry | Determines chiral purity by measuring rotation of plane-polarized light at specified wavelength and temperature. |
| Appearance | Visual Inspection | Assesses physical state, color, and clarity against established reference standards under controlled lighting. |
| Melting Point | Capillary Melting Point Determination | Identifies purity and identity by observing temperature range of solid-to-liquid phase transition. |
| Solvent Residues | Gas Chromatography (GC) with Headspace Sampling | Detects and quantifies residual solvents (e.g., methanol, THF) using volatile partitioning into headspace. |
| pH of Aqueous Solution | Potentiometric pH Measurement | Measures hydrogen ion activity in a defined aqueous suspension using calibrated pH electrode. |
| Test Item | Specification |
|---|---|
| Appearance | Colorless liquid |
| Purity | >=98.0% (GC-MS) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Odor | Characteristic ester-like odor |
| Refractive Index (n20/D) | 1.435–1.445 |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Danger |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.