4-Amino-3,5-difluorobenzonitrile Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 110301-23-0 |
| Product name | 4-Amino-3,5-difluorobenzonitrile |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty GradeIndustrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 4-Amino-3,5-difluorobenzonitrile
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 4-Amino-3,5-difluorobenzonitrile Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 4-Amino-3,5-difluorobenzonitrile
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Key intermediate for synthesizing antitumor agents or kinase inhibitors | Constructs fluorinated aromatic heterocyclic structures via nucleophilic substitution, reduction, or coupling reactions |
| Agrochemicals | Used to synthesize high-efficiency fluorinated insecticides or herbicide active ingredients | Participates in aryl nitrile group transformations and directed modifications of fluorinated aniline derivatives |
| Materials Science | Monomeric precursor for liquid crystal materials or organic optoelectronic materials | Derivatizes the cyano functional group to build fluorinated aromatic frameworks with rigid orientation |
| Fine Chemicals | High-value fluorinated intermediate for multistep synthesis | Leverages dual amino and cyano functionalities for selective protection/deprotection and functional group interconversion |
Manufacturing Quality Control of 4-Amino-3,5-difluorobenzonitrile
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 220-254 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC-UV; identification based on retention time matching and threshold limits per ICH Q3A/B. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify common solvents (e.g., acetone, methanol, toluene) against calibrated standards. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to determine trace water content via stoichiometric reaction. |
| Heavy Metals | ICP-OES | Multi-element quantification of Pb, Cd, Hg, As, and others after acid digestion, based on atomic emission intensity at characteristic wavelengths. |
| Chloride Impurity | Ion Chromatography | Separation and conductivity detection of chloride ions in aqueous extract; quantified against NaCl calibration curve. |
| Sulfated Ash | Gravimetric Analysis | Ignition at 750 C followed by sulfuric acid treatment and final weighing of non-volatile residue as percentage of sample mass. |
| Melting Point | Capillary Melting Point Apparatus | Determination of temperature range at which solid transitions to liquid, using calibrated digital apparatus per USP <741>. |
| Appearance | Visual Inspection | Assessment of physical state, color, and presence of foreign particles under controlled white light against defined reference standards. |
| Particle Size Distribution | Laser Diffraction | Measurement of particle size distribution in dry or dispersed state using Mie scattering theory and calibrated optical model. |
| Bulk Density | Tap Density Tester | Determination of mass per unit volume after standardized tapping per USP <616>; reported as both bulk and tapped density. |
| Organic Volatile Impurities (OVI) | GC-MS | Identification and quantification of unidentified volatile organic impurities using gas chromatography coupled with mass spectrometry detection. |
Technical Specifications of 4-Amino-3,5-difluorobenzonitrile
| Test Item | Specification |
|---|---|
| Appearance | Brown solid |
| Purity | >=98.0% (GC-MS) |
| Melting Point | 128–132°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Identification (IR) | Consistent with structure |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 4-Amino-3,5-difluorobenzonitrile
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 4-Amino-3,5-difluorobenzonitrile
Safety Information of 4-Amino-3,5-difluorobenzonitrile
| Pictograms |  |
| Signal Word | Danger |
| Safety Data Sheet | |
Packaging of 4-Amino-3,5-difluorobenzonitrile
Industrial 4-Amino-3,5-difluorobenzonitrile Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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