2-Chloro-4,5-difluorobenzoic acid Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 110877-64-0 |
| Product name | 2-Chloro-4,5-difluorobenzoic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeMaterial GradeSpecialty GradeIndustrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 2-Chloro-4,5-difluorobenzoic acid
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 2-Chloro-4,5-difluorobenzoic acid Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 2-Chloro-4,5-difluorobenzoic acid
| Industry | Application | Process |
|---|---|---|
| Pesticides | Intermediate for synthesizing novel fluorinated benzoic acid-based insecticides | Preparation of 2-chloro-4,5-difluorobenzoic acid via chlorination and fluorination reactions; used in subsequent condensation with amines to produce amide-type pesticide active ingredients |
| Pharmaceuticals | Intermediate for anticancer and anti-inflammatory drugs | Synthesis of fluorinated aromatic acid-containing drug molecules; complex molecular frameworks are typically constructed via coupling reactions (e.g., Suzuki or Stille coupling) |
| Polymers | Monomer for fluorinated functional polymers | Incorporated into polymer backbones via esterification or amidation to enhance thermal resistance and chemical stability |
| Dyes | Intermediate for fluorinated dyes | Synthesis of fluorescent dyes exhibiting superior lightfastness and color fastness; dye parent structures are linked via coupling reactions |
Manufacturing Quality Control of 2-Chloro-4,5-difluorobenzoic acid
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification based on peak area comparison against a certified reference standard using reversed-phase chromatography and UV detection at ~230 nm. |
| Related Substances | HPLC-UV or HPLC-MS | Separation and identification/quantification of structurally related impurities (e.g., mono-fluoro isomers, chlorinated by-products) using gradient elution and UV or mass-selective detection. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection to quantify residual solvents (e.g., methanol, acetone, toluene) per ICH Q3C guidelines. |
| Heavy Metals | ICP-MS | Multi-element quantification of toxic elements (e.g., Pb, Cd, Hg, As) after acid digestion, based on elemental mass spectrometric detection. |
| Chloride Content | Ion Chromatography (IC) | Separation and quantification of chloride anion via suppressed conductivity detection following aqueous extraction. |
| Moisture Content | Karl Fischer Titration (Coulometric) | Electrochemical titration measuring water content based on the stoichiometric reaction of iodine with water in a pyridine–methanol–SO₂ medium. |
| Melting Point | Capillary Melting Point Apparatus | Determination of solid-to-liquid phase transition temperature using controlled heating and optical observation of meniscus collapse. |
| Appearance | Visual Inspection | Assessment of physical state, color, and presence of foreign particles under standardized white light against a white/black background. |
| Residue on Ignition | Gravimetric Analysis (Weight Loss on Ignition) | Measurement of inorganic residue remaining after high-temperature ashing (500–600 °C) of a weighed sample. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light induced by chiral impurities or enantiomeric excess (though compound is achiral, method verifies absence of optically active contaminants). |
Technical Specifications of 2-Chloro-4,5-difluorobenzoic acid
| Test Item | Specification |
|---|---|
| Appearance | Off-white crystalline solid |
| Purity | >=98.0% (by LC-MS) |
| Melting Point | 142–146°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 2-Chloro-4,5-difluorobenzoic acid
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 2-Chloro-4,5-difluorobenzoic acid
Safety Information of 2-Chloro-4,5-difluorobenzoic acid
| Pictograms |  |
| Signal Word | Danger |
| Safety Data Sheet | |
Packaging of 2-Chloro-4,5-difluorobenzoic acid
Industrial 2-Chloro-4,5-difluorobenzoic acid Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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