Fmoc-O-trityl-L-serine Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 111061-56-4 |
| Product name | Fmoc-O-trityl-L-serine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for Fmoc-O-trityl-L-serine
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk Fmoc-O-trityl-L-serine Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of Fmoc-O-trityl-L-serine
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | As a protecting amino acid derivative in peptide synthesis, for incorporation of serine residues in solid-phase peptide synthesis (SPPS) | Stepwise coupling and deprotection under the Fmoc/tBu strategy, compatible with automated peptide synthesizers |
| Biochemical Research | Construction of custom peptides containing phosphoserine mimetics or glycosylation sites, for signaling pathway and enzymology studies | Selective trityl deprotection following solid-phase synthesis, followed by downstream modifications (e.g., phosphorylation, glycosylation) |
| Medicinal Chemistry | Synthesis of core building blocks for kinase-targeting compounds, protein-protein interaction inhibitors, or peptide-based drug candidates | Complex peptide chain assembly via Fmoc-SPPS platform with other protected amino acids, followed by global deprotection and purification |
| Diagnostics Reagent Development | Preparation of antigenic epitope peptides or antibody-binding peptides for immunoassays and disease biomarker research | Assembly of linear or cyclic peptides containing this residue on resin, followed by cleavage, purification, and use in assay plate coating or probe labeling |
Manufacturing Quality Control of Fmoc-O-trityl-L-serine
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component by UV absorption at 268 nm using reverse-phase C18 column and gradient elution with acetonitrile/water/TFA. |
| Related Substances | HPLC-UV | Detects and quantifies structurally related impurities (e.g., Fmoc-Ser-OH, trityl ether hydrolysis products) using validated HPLC method. |
| Residual Solvents | GC-FID | Measures residual solvents (e.g., DMF, DCM, methanol) by gas chromatography with flame ionization detection. |
| Water Content | Karl Fischer Titration | Determines water content via coulometric or volumetric titration using iodine-based redox reaction in pyridine/methanol medium. |
| Optical Rotation | [alpha]D Measurement | Measures specific optical rotation at 589 nm to confirm chiral integrity and enantiomeric purity. |
| Heavy Metals | ICP-MS | Quantifies trace heavy metals (Pb, Cd, Hg, As) after acid digestion using inductively coupled plasma mass spectrometry. |
| Residual Palladium | ICP-MS | Detects residual Pd from coupling catalysts using ICP-MS after microwave-assisted acid digestion. |
| Chloride Content | Ion Chromatography | Quantifies chloride ions using suppressed conductivity detection after aqueous extraction. |
| Residual Triphenylmethanol | HPLC-UV | Identifies and quantifies triphenylmethanol impurity using same HPLC system as assay with adjusted gradient. |
| Appearance | Visual Inspection | Assesses physical state, color, and presence of foreign particles under controlled white light against standard reference. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range of solid-to-liquid phase transition using calibrated capillary apparatus per USP <741>. |
| pH of Solution | pH Meter | Measures pH of a 1% w/v solution in water to detect acidic/basic degradation products. |
Technical Specifications of Fmoc-O-trityl-L-serine
| Test Item | Specification |
|---|---|
| Appearance | White Solid |
| Purity | ≥98.0% |
| Specific rotation at 20°C | [α]20/D +8.0±1 |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of Fmoc-O-trityl-L-serine
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of Fmoc-O-trityl-L-serine
Packaging of Fmoc-O-trityl-L-serine
Industrial Fmoc-O-trityl-L-serine Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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