China Factory Direct
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| CAS number | 111080-65-0 |
| Product name | 4-(BOC-AMINOMETHYL)PYRIDINE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Chemicals | Pyridine-based pharmaceutical intermediates | Serves as a pyridine-containing amine building block in drug molecule synthesis; amino group protection with BOC enables selective reactions. |
| Pharmaceutical Chemicals | Synthesis raw material for certain active pharmaceutical ingredients (APIs) | Used in the R&D and manufacturing of pyridylmethylamino-containing drugs; BOC deprotection followed by coupling with other drug fragments. |
| Biochemistry/Peptide Synthesis | Modification and synthesis of peptides or peptidomimetic compounds | Applied in solid-phase or solution-phase synthesis using BOC protection strategy to incorporate pyridylmethylamino groups into peptide sequences, thereby improving pharmacokinetic properties. |
| Organic Synthesis | Synthesis of specialty organic ligands | Employed in coordination chemistry synthesis to prepare organic ligands for metal-catalyzed reactions, leveraging both the coordinating ability of the pyridine ring and the derivatization capability of the amino group. |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 260 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC-UV; identification based on retention time relative to reference standards or threshold reporting. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify common solvents (e.g., THF, DMF, methanol) based on calibrated external standards. |
| Water Content | Karl Fischer Titration | Electrochemical titration using iodine generation to determine water content based on stoichiometric reaction with Karl Fischer reagent. |
| Heavy Metals | ICP-MS | Multi-element detection of toxic metals (e.g., Pb, Cd, Hg, As) after acid digestion, using isotopic mass spectrometry for sub-ppb sensitivity. |
| Chloride Content | Ion Chromatography | Separation and quantification of chloride ions using suppressed conductivity detection after aqueous extraction. |
| Residue on Ignition | Gravimetric Analysis | Measurement of inorganic ash content by ignition at 750 C and weighing the residual mass after cooling in a desiccator. |
| Optical Rotation | [alpha]D Measurement | Determination of specific optical rotation using a polarimeter at 20 C with sodium D-line (589 nm) to assess chiral purity and identity. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition detection via capillary method using controlled heating rate to confirm identity and crystallinity. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry powder dispersion using laser scattering to determine D10, D50, D90 values per USP <429>. |
| pH of Aqueous Suspension | Potentiometric pH Measurement | pH determination of a 1% w/v suspension in purified water using a calibrated pH electrode. |
| Microbial Contamination | Membrane Filtration | Quantitative enumeration of aerobic microorganisms using membrane filtration followed by incubation on soybean-casein digest agar per USP <61>. |
| Test Item | Specification |
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| Appearance | Pale-yellow solid |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 78–82°C |
| Identification (NMR) | Conforms to reference standard |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.