BIPHENYL-4-CARBOXAMIDINE HYDROCHLORIDE Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 111082-23-6 |
| Product name | BIPHENYL-4-CARBOXAMIDINE HYDROCHLORIDE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for BIPHENYL-4-CARBOXAMIDINE HYDROCHLORIDE
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk BIPHENYL-4-CARBOXAMIDINE HYDROCHLORIDE Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of BIPHENYL-4-CARBOXAMIDINE HYDROCHLORIDE
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate for the synthesis of the antiplatelet drug ticagrelor | Used as a key aryl amidine structural unit in the ticagrelor synthesis route, participating in coupling and cyclization reactions; typically prepared via iminodibenzylamine intermediate formation from 4-bromobenzonitrile using aqueous ammonia/sodium azide systems, followed by acid-catalyzed cyclization and hydrochloride salt formation, or directly synthesized from 4-cyanobiphenyl via the Pinner reaction |
| Organic Synthesis | Aryl amidine functional building block for constructing amidine-containing heterocyclic compounds (e.g., pyrimidine and triazine derivatives) | Applied in condensation and cycloaddition reactions with aldehydes, ketones, or carboxylic acid derivatives under basic conditions; commonly employed in structure-diversity synthesis for pharmaceutical chemistry and materials science |
Manufacturing Quality Control of BIPHENYL-4-CARBOXAMIDINE HYDROCHLORIDE
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 254 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of structurally related impurities using gradient HPLC with UV detection and relative response factors. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection to quantify volatile organic solvents based on retention time and peak area calibration. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to determine water content via stoichiometric reaction with iodine and sulfur dioxide. |
| Heavy Metals | ICP-OES | Multi-element quantification of toxic metals (e.g., Pb, Cd, Hg, As) after acid digestion using inductively coupled plasma optical emission spectroscopy. |
| Chloride Content | Potentiometric Titration | Titration with silver nitrate using a silver indicator electrode to detect endpoint based on potential change due to AgCl precipitation. |
| Residue on Ignition | Gravimetric Analysis | Weighing residue remaining after high-temperature ashing (600-800 C) to assess inorganic impurities and non-volatile contaminants. |
| Melting Point | Capillary Melting Point Apparatus | Determination of temperature range at which solid transitions to liquid, indicating purity and identity consistency. |
| Appearance | Visual Inspection | Assessment of physical state, color, and homogeneity under controlled lighting against defined specifications (e.g., white to off-white crystalline powder). |
| pH of Aqueous Solution | pH Meter | Measurement of hydrogen ion activity in a standardized aqueous suspension (e.g., 1% w/v) using calibrated pH electrode. |
| Particle Size Distribution | Laser Diffraction | Analysis of scattered laser light intensity to determine volume-based particle size distribution in dry or wet dispersion. |
| Microbial Limits | Membrane Filtration | Enumeration of aerobic microorganisms and detection of specified pathogens using culture-based methods on appropriate agar media. |
Technical Specifications of BIPHENYL-4-CARBOXAMIDINE HYDROCHLORIDE
| Test Item | Specification |
|---|---|
| Appearance | Off-white solid |
| Purity | >=98.0% (HPLC) |
| Water Content (KF) | <=0.5% |
| Melting Point | 185-190 °C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of BIPHENYL-4-CARBOXAMIDINE HYDROCHLORIDE
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of BIPHENYL-4-CARBOXAMIDINE HYDROCHLORIDE
Safety Information of BIPHENYL-4-CARBOXAMIDINE HYDROCHLORIDE
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of BIPHENYL-4-CARBOXAMIDINE HYDROCHLORIDE
Industrial BIPHENYL-4-CARBOXAMIDINE HYDROCHLORIDE Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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