2-Chloro-5-ethylpyrimidine Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 111196-81-7 |
| Product name | 2-Chloro-5-ethylpyrimidine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 2-Chloro-5-ethylpyrimidine
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 2-Chloro-5-ethylpyrimidine Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 2-Chloro-5-ethylpyrimidine
| Industry | Application | Process |
|---|---|---|
| Pesticides | Key intermediate in the synthesis of the broad-spectrum fungicide azoxystrobin | Condensed with methyl methoxyacrylate under basic conditions to produce azoxystrobin |
| Pharmaceuticals | Used to synthesize pyrimidine derivatives for antitumor and antiviral agents | Serves as a chloroethyl substituent for pyrimidine ring side-chain construction; introduces ethyl functionality via coupling reactions (e.g., Suzuki or Heck coupling) |
| Organic Synthesis | Building-block reagent for functionalization of heterocyclic compounds | Prepares 2-substituted-5-ethylpyrimidine derivatives via nucleophilic substitution (e.g., with amines, alcohols, or thiols) |
Manufacturing Quality Control of 2-Chloro-5-ethylpyrimidine
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | Gas Chromatography (GC) with FID detector | Quantitative determination based on peak area comparison against a certified reference standard under validated chromatographic conditions. |
| Residual Solvents | Headspace Gas Chromatography (HS-GC) | Volatile organic impurities are partitioned into headspace and quantified using calibrated GC-FID or GC-MS. |
| Water Content | Karl Fischer Titration (Coulometric) | Electrochemical titration where iodine reacts stoichiometrically with water; endpoint detected amperometrically. |
| Heavy Metals (Pb, Cd, Hg, As) | ICP-MS | Multi-element detection via ionization in plasma and mass spectrometric quantification at isotopic masses. |
| Chloride Impurity | Ion Chromatography (IC) | Separation of anions on ion-exchange column followed by conductivity detection and quantification against chloride standard. |
| Related Substances | High Performance Liquid Chromatography (HPLC) with UV detection | Separation of structurally related impurities on reversed-phase column; detection at 254 nm or method-specific wavelength. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition observed visually as solid-to-liquid phase change under controlled heating rate. |
| Appearance | Visual Inspection | Assessment of physical state, color, and clarity against established reference standards under controlled lighting. |
| Residue on Ignition | Gravimetric Analysis | Mass of non-volatile inorganic residue determined after high-temperature ashing and cooling in desiccator. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light induced by chiral molecules in solution at specified concentration and path length. |
| pH of Aqueous Solution | Potentiometric pH Measurement | Hydrogen ion activity determined using calibrated glass electrode and pH meter in saturated aqueous suspension. |
| Particle Size Distribution | Laser Diffraction | Analysis of light scattering pattern from dispersed particles to calculate size distribution based on Mie theory. |
Technical Specifications of 2-Chloro-5-ethylpyrimidine
| Test Item | Specification |
|---|---|
| Appearance | Yellow liquid |
| Purity | >=98.0% (GC-MS) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Refractive Index (n20/D) | 1.505–1.515 |
| Relative Density (20°C/4°C) | 1.12–1.14 g/cm³ |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 2-Chloro-5-ethylpyrimidine
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 2-Chloro-5-ethylpyrimidine
Packaging of 2-Chloro-5-ethylpyrimidine
Industrial 2-Chloro-5-ethylpyrimidine Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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