FMOC-D-PHG-OH Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 111524-95-9 |
| Product name | FMOC-D-PHG-OH |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeMaterial GradeSpecialty GradeReagent Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for FMOC-D-PHG-OH
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk FMOC-D-PHG-OH Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of FMOC-D-PHG-OH
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Used as a chiral synthetic intermediate for the preparation of active pharmaceutical ingredients (APIs), including antibiotics and antitumor agents | Applied in solid-phase and liquid-phase synthesis |
| Biochemistry | Employed as an amino acid protecting group in peptide synthesis, particularly in solid-phase peptide synthesis (SPPS) | Implemented via the Fmoc protection strategy |
| Materials Science | Served as a precursor for functional materials, enabling the preparation of optically active polymers or nanomaterials | Utilized in polymerization reactions and molecular self-assembly |
| Research Reagents | Used in organic chemistry research for asymmetric synthesis and chiral resolution experiments | Applied in catalytic reactions and chromatographic separation |
Manufacturing Quality Control of FMOC-D-PHG-OH
| Test Item | Common Testing Methods | Method Description |
|---|---|---|
| Appearance | Visual Inspection | Observe the color, state (e.g., white to off-white crystalline powder), and presence of visible foreign matter with the naked eye, in accordance with pharmacopoeia or enterprise standards. |
| Identification | Infrared Spectroscopy (IR) ¹H Nuclear Magnetic Resonance (¹H NMR) High-Performance Liquid Chromatography (HPLC) |
IR: Measure the infrared absorption spectrum of the sample and compare it with the reference standard; ¹H NMR: Analyze characteristic proton signals to confirm molecular structure; HPLC: Retention time under specific chromatographic conditions matches that of the reference standard. |
| Content Determination | High-Performance Liquid Chromatography (HPLC) | Use a reverse-phase C18 column with an appropriate mobile phase (e.g., acetonitrile-water or methanol-phosphate buffer) for isocratic or gradient elution. Detect using a UV detector (typically 210–260 nm) and calculate the content of the main component by external standard method. |
| Related Substances (Impurities) | High-Performance Liquid Chromatography (HPLC) | Use high-resolution reverse-phase HPLC to detect and quantify process impurities and degradation products, typically setting total impurity limits and individual impurity limits. |
| Optical Rotation | Spectropolarimetry | Determine the optical rotation of a solution at a specified concentration and wavelength (usually sodium D line, 589 nm) and temperature, to verify optical purity (as the compound is D-configured). |
| Loss on Drying | Thermogravimetric Analysis (TGA) or Constant Pressure Drying Method | Dry the sample at 105°C until constant weight is achieved and measure the percentage of mass loss to evaluate moisture and volatile substances content. |
| Residue on Ignition | Gravimetric Method | Weigh the residue after incinerating the sample at high temperature (~700–800°C) to control inorganic impurities. |
| Moisture | Karl Fischer Titration (KFT) | Use volumetric or coulometric KF titration to accurately determine the water content in the sample, suitable for moisture-sensitive protected amino acid derivatives. |
| Residual Solvents | Gas Chromatography (GC) | GC with headspace injection or direct injection to detect residual organic solvents from the synthesis process (e.g., dichloromethane, methanol, ethyl acetate), complying with ICH Q3C guidelines. |
| pH Value (if prepared as a solution) | pH Meter Method | Prepare the sample as a water solution at a specified concentration and use a calibrated pH meter to measure its pH value, evaluating acidity or alkalinity according to requirements. |
Technical Specifications of FMOC-D-PHG-OH
| Test Item | Specification |
|---|---|
| Appearance | Off-white solid |
| Purity | >=98.0% (LC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 168–172°C |
| Optical Rotation | +15.0 to +17.0° (c=1, DMF) |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of FMOC-D-PHG-OH
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of FMOC-D-PHG-OH
Packaging of FMOC-D-PHG-OH
Industrial FMOC-D-PHG-OH Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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