China Factory Direct
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| CAS number | 111600-83-0 |
| Product name | 5-bromo-4-methylthiazole |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty Grade |
| Packaging | 25L/drum |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Antibacterial drug intermediate for synthesizing thiazole-based antibiotics (e.g., cephalosporin derivatives) | Undergoes nucleophilic substitution with amines in inert solvents (e.g., THF or DMF) to form C–N bonds |
| Pesticides | Key intermediate for fungicides and insecticides, used in producing novel thiazole-based agrochemicals | Condenses and cyclizes with aromatic aldehydes to yield thiazoline active ingredients |
| Materials Science | Building block for electron-transport layer materials in organic light-emitting diode (OLED) devices | Introduces conjugated aryl groups via Suzuki or Stille coupling to tune energy levels and charge-carrier mobility |
| Detection Item | Common Analytical Method | Method Overview |
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| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at ~254 nm, comparing peak area against a certified reference standard. |
| Related Substances (Impurities) | HPLC-UV or UPLC-MS | Separation and quantification of structurally related impurities (e.g., bromination by-products, des-bromo analogs) using gradient HPLC/UPLC, with UV or mass spectrometric detection. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection to quantify residual solvents (e.g., methanol, ethyl acetate, toluene) per ICH Q3C guidelines. |
| Heavy Metals (Total) | ICP-MS | Multi-element quantification of toxic metals (e.g., Pb, Cd, Hg, As) after acid digestion, based on USP <232>/<233> and ICH Q3D. |
| Moisture Content | Karl Fischer Titration (Coulometric) | Electrochemical titration measuring water content via iodine generation and stoichiometric reaction with water in anhydrous medium. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition determination by observing solid-to-liquid phase change under controlled heating rate, per USP <741>. |
| Chloride Impurity | Ion Chromatography (IC) with Conductivity Detection | Separation and quantification of chloride ions using anion-exchange column and suppressed conductivity detection, aligned with EP 2.4.18. |
| Residue on Ignition | Gravimetric Analysis (Weight Loss on Ignition) | Measurement of non-volatile inorganic residue after high-temperature ashing (700–800 °C), per USP <281>. |
| Test Item | Specification |
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| Appearance | Yellow liquid |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 42–46°C |
| Identification (NMR) | Consistent with structure |
| Identification (IR) | Consistent with structure |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.