4-Bromopyridine Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 1120-87-2 |
| Product name | 4-Bromopyridine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 4-Bromopyridine
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 4-Bromopyridine Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 4-Bromopyridine
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Chemicals | Pharmaceutical Intermediate | Serves as a key structural unit in Suzuki coupling or nucleophilic substitution reactions to synthesize biologically active pyridine-containing drug molecules (e.g., pyridine-ring inhibitors, analgesics). |
| Agrochemicals | Agrochemical Intermediate | Introduces the pyridyl group via C–N coupling or etherification to synthesize high-efficacy, low-toxicity fungicides, insecticides, or herbicides (e.g., novel pyridine-based agrochemicals). |
| Materials Chemicals | Intermediate for Organic Optoelectronic Materials | Leverages bromine reactivity to construct conjugated macromolecules or functionalized ligands for organic light-emitting diode (OLED) or organic semiconductor materials. |
| Organic Synthesis | Raw Material for Catalyst/Ligand Synthesis | Used to synthesize pyridine-based ligands (e.g., bipyridine derivatives), which are subsequently complexed with metals to prepare homogeneous reaction catalysts. |
| Analytical Chemistry | Derivative of Analytical Reagent | Acts as a derivatization reagent to synthesize structurally defined probe molecules for metal ion detection or bioimaging analysis. |
Manufacturing Quality Control of 4-Bromopyridine
| Detection Item | Common Detection Methods | Method Overview |
|---|---|---|
| Appearance | Visual Inspection | Observe the color, physical state, and clarity of the sample. 4-Bromopyridine is typically a colorless to pale yellow liquid or crystal. |
| Content (Purity) | Gas Chromatography (GC) | Utilize capillary column gas chromatography with internal or external standard methods to determine the main component content and assess purity. Suitable for volatile organic compounds. |
| High-Performance Liquid Chromatography (HPLC) | Use a reversed-phase C18 column with a UV detector (e.g., 254 nm) to quantify the main component based on retention time and peak area. | |
| Structure Confirmation | Nuclear Magnetic Resonance Spectroscopy (NMR) | Perform ¹H-NMR and ¹³C-NMR analyses to confirm the molecular structure, verifying the substitution position and chemical environment consistent with 4-bromopyridine. |
| Fourier Transform Infrared Spectroscopy (FT-IR) | Analyze characteristic absorption peaks of functional groups to verify the presence of the pyridine ring and C-Br bond. | |
| Mass Spectrometry (MS) | Determine the molecular ion peak via EI-MS or ESI-MS (m/z ≈ 172/174 [M⁺]) to confirm molecular weight and isotopic distribution. | |
| Water Content | Karl Fischer Titration (KF) | Quantitatively measure trace water content in the sample using Karl Fischer reagent, suitable for controlling water in organic solvents. |
| Residual Solvents | Gas Chromatography (GC) | Detect possible residual organic solvents (e.g., methanol, ethanol, acetone, dichloromethane) from the manufacturing process, in accordance with ICH guidelines. |
| Bromine Content | Ion Chromatography or Elemental Analysis | Determine the bromine element content in the sample to verify consistency with the theoretical value (~46.3%). |
| pH Value (in Solution) | pH Meter Measurement | Dissolve the sample in water at a specified concentration (considering solubility), and measure acidity/basicity using a calibrated pH meter. |
| Heavy Metal Impurities | Atomic Absorption Spectroscopy (AAS) or Inductively Coupled Plasma Mass Spectrometry (ICP-MS) |
Detect toxic metal residues such as lead, mercury, cadmium, and chromium to ensure compliance with pharmacopoeial or safety standards. |
| Melting/Boiling Point | Melting Point Apparatus or Boiling Point Apparatus | Measure physical constants as an auxiliary identification method. The melting point of 4-bromopyridine is approximately 20–25°C (may appear oily in liquid state); boiling point is approximately 200°C. |
Technical Specifications of 4-Bromopyridine
| Test Item | Specification |
|---|---|
| Appearance | Red-brown liquid |
| Purity | >=98.0% (GC-MS) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Melting Point | -15 to -10°C |
| Refractive Index (n20/D) | 1.555–1.565 |
| Relative Density (20°C/25°C) | 1.54–1.56 g/cm³ |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 4-Bromopyridine
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 4-Bromopyridine
Packaging of 4-Bromopyridine
Industrial 4-Bromopyridine Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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