China Factory Direct
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| CAS number | 112068-01-6 |
| Product name | (S)-(-)-α,α-Diphenyl-2-pyrrolidinemethanol |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Material GradeSpecialty GradeIndustrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Chemistry | Chiral auxiliaries or chiral ligands for asymmetric synthesis of pharmaceutical intermediates | Induces stereoselectivity in transition-metal-catalyzed or organocatalyzed reactions, such as asymmetric hydrogenation and alkylation |
| Organic Synthesis | Chiral catalyst precursors for asymmetric catalytic reactions | Forms chiral catalysts upon complexation with metals (e.g., zinc, titanium), applied in asymmetric additions to aldehydes (e.g., Reformatsky reaction, allylation) |
| Fine Chemicals | Key chiral building blocks for synthesizing optically active compounds | Serves as a chiral auxiliary in constructing complex molecular frameworks, followed by cleavage and recovery |
| Materials Science | Preparation of chiral functional materials or liquid crystal precursors | Introduces chiral centers via derivatization to modulate optical properties or self-assembly behavior of materials |
| Test Item | Common Testing Method | Method Overview |
|---|---|---|
| Appearance | Visual Inspection | Observe the sample's color and physical state (typically white to off-white crystals or powder) to determine compliance with standard requirements. |
| Melting Point | Capillary Melting Point Method | Determine the melting temperature range using a melting point apparatus; compare with literature values (approximately 102–105 °C) to assess purity. |
| Specific Optical Rotation | Polarimetry | Prepare a solution of specified concentration and measure the specific optical rotation at a defined wavelength (typically sodium D line, 589 nm) and temperature to verify optical purity and configuration ([α]D²⁵ ≈ +75° to +80°, c=1 in MeOH). |
| Identification | Fourier Transform Infrared Spectroscopy (FT-IR) | Obtain the infrared spectrum of the sample and compare characteristic absorption peaks (e.g., O-H, N-H, C-O, aromatic rings) with reference spectra to confirm molecular structure. |
| Identification / Purity | Proton Nuclear Magnetic Resonance (¹H NMR) | Record the ¹H NMR spectrum in a deuterated solvent (e.g., CDCl₃); confirm molecular structure and detect impurities based on chemical shifts, integration, and coupling constants. |
| Assay (Content Determination) | High-Performance Liquid Chromatography (HPLC) | Use a reversed-phase C18 column with methanol/water or acetonitrile/water as mobile phase and a UV detector (~210–260 nm) to quantify the main component; typically requires ≥98.0%. |
| Optical Purity (Enantiomeric Excess) | Chiral High-Performance Liquid Chromatography (Chiral HPLC) | Use a chiral stationary phase column (e.g., Chiralpak AD-H, OD-H) to separate enantiomers and calculate enantiomeric excess (e.e. ≥99%). |
| Residual Solvents | Gas Chromatography (GC) | Use headspace or direct injection with an FID detector to determine residual organic solvents (e.g., methanol, ethanol, dichloromethane) from synthesis or purification processes. |
| Loss on Drying | Thermogravimetric Analysis (TGA) or Oven Drying Method | Dry the sample at a specified temperature (e.g., 105 °C) to constant weight and measure weight loss to evaluate moisture and volatile content (typically ≤0.5%). |
| Sulfated Ash / Residue on Ignition | High-Temperature Ignition Method | Ignite the sample at high temperature (approx. 600–800 °C), then weigh the residue to determine inorganic impurity levels (typically ≤0.1%). |
| Heavy Metals | Atomic Absorption Spectroscopy (AAS) or Inductively Coupled Plasma Mass Spectrometry (ICP-MS) | Digest the sample and measure concentrations of heavy metal elements such as lead, arsenic, mercury, and cadmium to ensure compliance with pharmacopoeial or ICH limits. |
| Test Item | Specification |
|---|---|
| Appearance | White to yellow crystalline powder |
| Purity | >=98.0% (HPLC) |
| Optical Rotation | -62.0 to -56.0 deg (c=1, in CHCl3) |
| Melting Point | 128.0 to 132.0 °C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.