China Factory Direct
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| CAS number | 1122-44-7 |
| Product name | 5-IODOCYTOSINE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Synthetic intermediate for antiviral drugs, used in the preparation of anti-herpes and anti-cytomegalovirus agents | Iodination reaction in chemical synthesis; serves as a nucleoside analog precursor |
| Biochemical Research | Nucleoside analog employed to study DNA synthesis, repair, and cellular proliferation mechanisms | Used as a tracer or inhibitor in cell culture or in vitro experiments |
| Diagnostics Reagents | Radiolabeled probe (e.g., iodine-125 labeled) for detection of specific biomolecules | Isotope labeling technique integrated with nucleic acid detection or imaging processes |
| Agricultural Research | Viral inhibition assays or gene expression analysis in plant pathology studies | Laboratory-scale bioassays or molecular biology processing |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies 5-iodocytosine by separation on a reversed-phase column and UV detection at ~280 nm, comparing peak area to a calibrated standard. |
| Related Substances | HPLC-UV | Detects and quantifies structurally related impurities (e.g., unreacted cytosine, iodination by-products) using gradient HPLC with UV detection. |
| Residual Solvents | GC-FID | Identifies and quantifies residual solvents (e.g., DMF, acetonitrile, methanol) by gas chromatography with flame ionization detection. |
| Water Content | Karl Fischer Titration | Determines trace water via coulometric or volumetric titration using iodine generated electrochemically in the presence of water. |
| Heavy Metals | ICP-MS | Measures trace metal contaminants (e.g., Pb, Cd, Hg, Ni) by inductively coupled plasma mass spectrometry after acid digestion. |
| Residue on Ignition | Gravimetric Analysis | Measures non-volatile inorganic residue after high-temperature ashing (500–600 C) and weighing. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range at which solid transitions to liquid, indicating purity and identity via thermal behavior. |
| Specific Optical Rotation | Polarimetry | Measures rotation of plane-polarized light to confirm chiral integrity and enantiomeric purity (though 5-iodocytosine is achiral, detects chiral impurities). |
| Particle Size Distribution | Laser Diffraction | Analyzes dry or wet dispersion to determine D10, D50, D90 values for consistency in downstream processing. |
| pH of Aqueous Suspension | pH Meter | Measures hydrogen ion activity in a defined suspension (e.g., 1% w/v in water) to assess acidic/basic degradation products. |
| Loss on Drying | Thermogravimetric Analysis (TGA) | Quantifies volatile content (e.g., solvent, moisture) by mass loss upon controlled heating (e.g., 105 C, 2 h). |
| Microbial Limits | Membrane Filtration and Plate Count | Detects and enumerates aerobic bacteria, yeasts, and molds using selective agar media after filtration and incubation. |
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.0% (HPLC) |
| Melting Point | 235–239 °C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Heavy Metals | <=10 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.