China Factory Direct
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| CAS number | 1122-54-9 |
| Product name | 4-Acetylpyridine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty GradeReagent Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Used as a pharmaceutical intermediate in the synthesis of antitumor, antiviral, and neurosystem-related drugs | Active molecular scaffolds are constructed via nucleophilic substitution, reduction, or condensation reactions |
| Agrochemicals | Used as an agrochemical intermediate in the synthesis of biologically active heterocyclic compounds | Functional groups are introduced through acylation, alkylation, and related reactions |
| Chemical Research | Used as an organic synthesis reagent and ligand precursor for constructing metal complexes | Coordinates with transition metals (e.g., ruthenium, palladium) to form catalytic or luminescent materials |
| Materials Science | Used in the preparation of functional polymers or optoelectronic materials | Participates in polymerization or copolymerization reactions to incorporate pyridine functional units for performance tuning |
| Test Item | Common Testing Methods | Method Overview |
|---|---|---|
| Appearance | Visual Inspection | Observe the color, state, and visible impurities of the sample under natural light or standard illumination. |
| Content Determination | Gas Chromatography (GC) | Use a capillary column gas chromatograph with a hydrogen flame ionization detector (FID), quantifying 4-acetylpyridine using external or internal standard methods. |
| High-Performance Liquid Chromatography (HPLC) | Use a C18 reversed-phase column with a ultraviolet detector (UV, typically at 254 nm or 280 nm), employing a methanol/water or acetonitrile/water mobile phase system for quantitative analysis. | |
| Purity Analysis | Gas Chromatography-Mass Spectrometry (GC-MS) | Combine GC separation capabilities with MS identification to determine the structure of main components and impurities, assessing purity and impurity profile. |
| HPLC-DAD | Use a diode array detector to obtain UV spectra of impurities, assisting in qualitative analysis and evaluating total purity. | |
| Water Content | Karl Fischer Titration | Use volumetric or coulometric methods to determine the water content in the sample, suitable for trace water analysis. |
| Residual Solvents | Gas Chromatography (GC) | Detect residual organic solvents from production using headspace-GC according to pharmacopoeia (e.g., Chinese Pharmacopoeia, USP). |
| Heavy Metals | Atomic Absorption Spectroscopy (AAS) | Determine the levels of heavy metals such as lead, cadmium, and mercury after sample digestion. |
| Inductively Coupled Plasma Mass Spectrometry (ICP-MS) | More sensitive detection of multiple trace metal impurities, suitable for high-purity product requirements. | |
| pH Value (in solution) | pH Meter Measurement | Dissolve a certain concentration of 4-acetylpyridine solution in water or an appropriate solvent, and measure its pH using a calibrated pH meter. |
| Melting Point/Boiling Point | Melting Point Apparatus or Differential Scanning Calorimetry (DSC) | Determine the melting temperature range to assess crystallinity and purity; boiling point can be confirmed by distillation or literature comparison. |
| Impurity Limit Testing | HPLC or GC | Estimate the content of related substances by comparing with known impurity reference standards or using peak area normalization method, controlling individual and total impurities. |
| Test Item | Specification |
|---|---|
| Appearance | Colorless to light yellow clear liquid |
| Purity | >=98.5% (GC) |
| Water Content (KF) | <=0.5% |
| Melting Point | -15 to -10°C |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Residue on Ignition | <=0.1% |
| Odor | Characteristic pyridine-like odor |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.