China Factory Direct
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| CAS number | 1122-96-9 |
| Product name | 4-Methoxypyridine N-oxide |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeReagent GradeCosmetic GradeFood Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Synthesis of pharmaceutical intermediates for antiviral and antitumor drugs | Produced via oxidation of 4-methoxypyridine to form the N-oxide |
| Pesticides | Synthesis of pesticide intermediates for novel insecticides and herbicides | Used as a precursor in heterocyclic compound synthesis, participating in multistep organic reactions |
| Fragrances | Intermediate in fragrance synthesis for custom scent formulation | Employed in aromatic compound synthesis to enhance fragrance stability and volatility |
| Chemical Reagents | Research and analytical testing in laboratory settings | Utilized as a standard reagent or synthetic intermediate in chromatographic analysis or organic synthesis experiments |
| Test Item | Common Analytical Methods | Method Description |
|---|---|---|
| Identification (Identity) | Infrared Spectroscopy (IR) Proton Nuclear Magnetic Resonance (¹H NMR) Mass Spectrometry (MS) |
The compound structure is confirmed as 4-methoxypyridine N-oxide by comparing characteristic IR absorption peaks, ¹H NMR chemical shifts and coupling constants, and mass spectral molecular ion peaks with standard spectra. |
| Assay (Content Determination) | High-Performance Liquid Chromatography (HPLC) | A reversed-phase C18 column is used with an appropriate water-organic solvent mixture (e.g., methanol or acetonitrile) as the mobile phase. The main component content is calculated using a UV detector (typically at 254 nm) with external standard method or area normalization method. |
| Related Substances/Impurity Testing | High-Performance Liquid Chromatography (HPLC) | Similar or optimized chromatographic conditions to those used in the assay are applied to separate and detect potential process impurities (e.g., unreacted starting material 4-methoxypyridine, by-products, etc.) and degradation products. Quantification is performed using self-comparison method or principal component self-comparison method with correction factor. |
| Residual Solvents | Gas Chromatography (GC) | Following ICH Q3C guidelines, headspace or direct injection methods are employed with polar or non-polar capillary columns and FID detector to qualitatively and quantitatively analyze residual organic solvents from the synthesis process (e.g., dichloromethane, methanol, acetonitrile, etc.). |
| Water Content | Karl Fischer Titration | Sample water content is accurately measured using volumetric or coulometric Karl Fischer titration to meet pharmacopoeia or internal control standards (usually ≤0.5%). |
| Loss on Drying | Thermogravimetric Analysis (TGA) or Conventional Drying Method | At specified temperature (e.g., 105°C), the sample is dried until constant weight to determine the total mass loss due to volatile substances (including water and other volatile impurities). |
| Melting Point | Capsule Melting Point Determination | A melting point apparatus is used to measure the initial to final melting temperature range, which is compared to literature values (approximately 110–114°C) as an auxiliary indicator for purity and identity. |
| Appearance and Properties | Visual Inspection | Observe sample color (typically white to off-white crystalline powder), odor, and physical state to ensure they conform to standard descriptions. |
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow solid |
| Purity | >=98.0% (by LC-MS) |
| Melting Point | 78–82°C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.