China Factory Direct
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| CAS number | 112246-73-8 |
| Product name | (+)-Diisopinocampheyl chloroborane |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Reagent GradeIndustrial GradeSpecialty Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Industry | Chiral reducing agent for asymmetric reduction of ketones to produce chiral secondary alcohols | React ketone substrates with (+)-diisopinocampheylchloroborane in toluene or dichloromethane at low temperature (–20 °C to 0 °C), followed by quenching with basic hydrogen peroxide to yield chiral alcohol products |
| Fine Chemicals | Chiral catalyst precursor for synthesizing chiral pharmaceutical intermediates | Participate in asymmetric hydroboration of alkenes as a borohydride reagent, followed by oxidation to yield chiral primary alcohols |
| Academic Research | Classic chiral reducing reagent in asymmetric synthesis, used for methodology development and mechanistic studies | Selectively reduce α,β-unsaturated carbonyl compounds via 1,2- or 1,4-addition under anhydrous, oxygen-free conditions to construct chiral centers |
| Test Item | Common Testing Methods | Method Overview |
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| Appearance and Physical Characteristics | Visual Inspection, Physical Observation | Observe the sample's color, physical state (typically a colorless to pale yellow liquid), transparency, and the presence of suspended particles or precipitates. Suitable for preliminary assessment of purity and storage stability. |
| Chiral Purity (Enantiomeric Excess, %ee) | Chiral Gas Chromatography (Chiral GC) or Chiral High-Performance Liquid Chromatography (Chiral HPLC) | Use chiral stationary phase columns to separate enantiomers. Compare retention times with reference standards to calculate enantiomeric excess (%ee), ensuring stereochemical integrity. |
| Chemical Purity | Nuclear Magnetic Resonance Spectroscopy (¹H NMR, ¹³C NMR) | Analyze the position, integration ratio, and splitting patterns of characteristic peaks to confirm molecular structure and assess impurity levels (e.g., solvents, by-products). |
| Assay (Content Determination) | Hydrolysis Titration or Quantitative NMR (qNMR) | Hydrolyze the sample to release HCl, then titrate with a standard base solution; or use internal standard qNMR to quantify the concentration of the active compound for accurate assay determination. |
| Chlorine Content | Elemental Analysis (EA) or Ion Chromatography | Determine the percentage of chlorine in the sample to verify the presence and quantity of chlorine as per theoretical values. |
| Volatile Impurities / Residual Solvents | Gas Chromatography (GC) | Detect residual solvents (e.g., hexane, diethyl ether) and ensure compliance with safety limits according to ICH guidelines. |
| Water Content | Karl Fischer Titration | Precisely measure moisture content, as the compound is water-sensitive and excessive moisture may lead to decomposition. |
| Thermal Stability | Differential Scanning Calorimetry (DSC) or Thermogravimetric Analysis (TGA) | Evaluate decomposition temperature and thermal stability to determine appropriate storage conditions and process safety. |
| Test Item | Specification |
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| Appearance | Colorless to light yellow liquid |
| Assay | 60 - 65% |
| Optical Rotation [a]20/D | ≥+45°,C=1 in Hexane |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Danger |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.