China Factory Direct
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| CAS number | 112346-82-4 |
| Product name | 3-CHLORO-D-ALANINE METHYL ESTER,HYDROCHLORIDE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Chiral synthetic intermediate | Used in the synthesis of β-lactam antibiotics and other serine-containing drug molecules, enabling stereocontrolled construction of chiral centers |
| Organic synthesis | Asymmetric synthesis reagent | Serves as a building block for chlorinated amino acid derivatives and participates in multistep organic transformations, including nucleophilic substitution and coupling reactions |
| Biochemistry | Enzyme inhibitor research | Applied in the design and synthesis of inhibitors targeting specific enzymes to investigate their mechanisms of action in metabolic pathways |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reversed-phase HPLC with UV detection at 210 nm, calibrated against certified reference standard. |
| Enantiomeric Purity | Chiral HPLC | Separates R- and S-enantiomers on a chiral stationary phase; peak area ratio determines enantiomeric excess. |
| Residual Solvents | GC-FID | Detects and quantifies volatile organic solvents (e.g., methanol, dichloromethane) using flame ionization detection after headspace sampling. |
| Water Content | Karl Fischer Titration | Measures water via coulometric or volumetric titration using iodine generation in pyridine-free reagent system. |
| Heavy Metals | ICP-MS | Quantifies trace metals (Pb, Cd, Hg, As, etc.) after acid digestion by detecting elemental ions based on mass-to-charge ratio. |
| Chloride Content | Potentiometric Titration | Determines chloride ion concentration using silver nitrate titrant and silver/silver chloride indicator electrode. |
| Residual Acid (HCl) | Acid-Base Titration | Titrates free HCl with standardized NaOH solution using phenolphthalein or potentiometric endpoint detection. |
| Related Substances | HPLC-UV | Identifies and quantifies structurally related impurities (e.g., dechlorinated, hydrolyzed, or dimeric species) using gradient elution. |
| Optical Rotation | [alpha]D Measurement | Measures specific rotation at 589 nm using sodium D-line to confirm chiral integrity and concentration-corrected identity. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range of solid-to-liquid transition using calibrated digital apparatus per USP <741>. |
| Particle Size Distribution | Laser Diffraction | Analyzes dry powder size distribution by measuring angular scattering pattern of laser beam through dispersed sample. |
| Microbial Limits | Membrane Filtration | Quantifies aerobic microorganisms and detects absence of specified pathogens (e.g., E. coli, Salmonella) per Ph. Eur. 2.6.12. |
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Optical Rotation | +6.0 to +9.0 deg (c=1, in H2O) |
| Melting Point | 148 to 152 °C |
| Identification (NMR) | Consistent with structure |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.