TRANS-CYCLOBUTANE-1,2-DICARBOXYLIC ACID Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 1124-13-6 |
| Product name | TRANS-CYCLOBUTANE-1,2-DICARBOXYLIC ACID |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Material GradeSpecialty GradeReagent GradeIndustrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for TRANS-CYCLOBUTANE-1,2-DICARBOXYLIC ACID
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk TRANS-CYCLOBUTANE-1,2-DICARBOXYLIC ACID Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of TRANS-CYCLOBUTANE-1,2-DICARBOXYLIC ACID
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Used as a chiral synthetic intermediate for preparing precursors to certain drug molecules (e.g., β-lactam antibiotics or cardiovascular agents) | Chiral resolution, asymmetric synthesis |
| Fine chemicals | Used as an organic building block to construct complex molecules containing cyclobutane structures | Multistep organic synthesis, cycloaddition reactions |
| Materials science | Applied in synthesizing functional polymers or liquid crystalline materials with defined stereochemistry | Polymerization, functionalization |
| Research | Used as a reference standard or model compound to study the stereochemistry and reactivity of cyclobutane derivatives | Analytical testing, mechanistic studies |
Manufacturing Quality Control of TRANS-CYCLOBUTANE-1,2-DICARBOXYLIC ACID
| Test Item | Common Testing Methods | Method Overview |
|---|---|---|
| Appearance and Physical Characteristics | Visual inspection, microscopic observation | Observe the sample's color, crystal form, and particle state using the naked eye or an optical microscope to determine whether the physical appearance meets the standard (e.g., white crystalline powder). |
| Identification | Infrared Spectroscopy (IR), Proton Nuclear Magnetic Resonance (¹H NMR) | Confirm whether the compound structure is trans-1,2-cyclobutanedicarboxylic acid by comparing characteristic IR absorption peaks or ¹H NMR chemical shifts with reference spectra. |
| Assay (Content Determination) | High-Performance Liquid Chromatography (HPLC), Acid-Base Titration | HPLC: Use a C18 reversed-phase column with a suitable mobile phase (e.g., phosphate buffer-methanol system), and quantify using a UV detector; Titration: Exploit its dicarboxylic acid properties by titrating with standardized NaOH solution to calculate the content of the main component. |
| Related Substances (Impurities) | High-Performance Liquid Chromatography (HPLC) | Use an HPLC system with gradient or isocratic elution to separate and detect impurities such as cis-isomers, degradation products, and other organic impurities. Quantification is typically performed using the area normalization method or the main component self-reference method with correction factors. |
| Water Content | Karl Fischer Titration | Quantitatively react the sample's water content with Karl Fischer reagent and determine moisture levels via coulometric or volumetric titration to control the product's degree of dryness. |
| Residual Solvents | Gas Chromatography (GC) | Use headspace or direct injection GC with polar or non-polar capillary columns and FID detection to analyze residual organic solvents (e.g., methanol, ethanol, acetone), ensuring compliance with ICH Q3C limits. |
| Melting Point | Capillary Melting Point Method | Pack the sample into a melting point capillary tube and observe the temperature range from initial melting to complete melting under controlled heating rate to verify purity and crystalline consistency. |
| pH Value | pH Meter Method | Prepare an aqueous solution of defined concentration (e.g., 1% w/v) and measure its pH using a calibrated pH meter to assess acidity strength and potential ionic impurities. |
| Sulfated Ash / Residue on Ignition | Gravimetric Method | Weigh the inorganic residue remaining after igniting the sample at high temperature (typically 700–800°C) to evaluate levels of inorganic impurities or residual metal catalysts. |
| Heavy Metals | Atomic Absorption Spectroscopy (AAS) or Inductively Coupled Plasma Mass Spectrometry (ICP-MS) | After acid digestion, determine the levels of heavy metal elements such as lead, cadmium, mercury, and arsenic using AAS or ICP-MS to ensure compliance with pharmacopoeial or regulatory limits. |
Technical Specifications of TRANS-CYCLOBUTANE-1,2-DICARBOXYLIC ACID
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.0% |
| Melting Point | 172-176°C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
| Acid Value (mg KOH/g) | 340-360 mg KOH/g |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of TRANS-CYCLOBUTANE-1,2-DICARBOXYLIC ACID
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of TRANS-CYCLOBUTANE-1,2-DICARBOXYLIC ACID
Safety Information of TRANS-CYCLOBUTANE-1,2-DICARBOXYLIC ACID
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of TRANS-CYCLOBUTANE-1,2-DICARBOXYLIC ACID
Industrial TRANS-CYCLOBUTANE-1,2-DICARBOXYLIC ACID Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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