8-Bromo-[1,2,4]triazolo[1,5-a]pyridin-2-ylamine Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 1124382-72-4 |
| Product name | 8-Bromo-[1,2,4]triazolo[1,5-a]pyridin-2-ylamine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 8-Bromo-[1,2,4]triazolo[1,5-a]pyridin-2-ylamine
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 8-Bromo-[1,2,4]triazolo[1,5-a]pyridin-2-ylamine Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 8-Bromo-[1,2,4]triazolo[1,5-a]pyridin-2-ylamine
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Chemicals | Drug discovery intermediates | Serves as a key building block in coupling reactions (e.g., Suzuki-Miyaura) or nucleophilic substitution reactions to construct drug molecules containing a thiazolopyridine scaffold. |
| Pharmaceutical Chemicals | Kinase inhibitor development | Applied in the synthesis of small-molecule kinase inhibitor candidates targeting specific kinases (e.g., PI3K, CDK). |
| Chemical Reagents | Synthesis of bioactive molecules | Used to construct libraries of pyrimidine or pyridylthiazole derivatives for high-throughput screening to identify compounds with potential antitumor or anti-inflammatory activity. |
Manufacturing Quality Control of 8-Bromo-[1,2,4]triazolo[1,5-a]pyridin-2-ylamine
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reversed-phase HPLC with UV detection at characteristic wavelength, calibrated against certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of structurally related impurities using gradient HPLC-UV, relative to main peak area. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection for identification and quantification of volatile organic solvents. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to determine trace water content based on stoichiometric reaction. |
| Heavy Metals | ICP-MS | Multi-element detection and quantification of toxic metals (e.g., Pb, Cd, Hg, As) after acid digestion and matrix separation. |
| Chloride Impurity | Ion Chromatography | Separation and quantification of chloride ions using suppressed conductivity detection after aqueous extraction. |
| Residue on Ignition | Gravimetric Analysis | Determination of inorganic ash content by high-temperature incineration followed by precise weighing of residual residue. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition measurement using controlled heating and visual observation of solid-to-liquid phase change. |
| Bulk Density | ASTM D1895 | Measurement of mass per unit volume for free-flowing powder using standardized graduated cylinder and tapping procedure. |
| Particle Size Distribution | Laser Diffraction | Analysis of particle size distribution based on angular dependence of laser light scattering in dispersed sample. |
| Optical Rotation | Polarimetry | Measurement of specific rotation using sodium D-line light to assess chiral purity and enantiomeric excess. |
| pH of Aqueous Suspension | pH Meter | Determination of surface acidity/basicity by measuring hydrogen ion activity in a defined aqueous suspension under standardized conditions. |
Technical Specifications of 8-Bromo-[1,2,4]triazolo[1,5-a]pyridin-2-ylamine
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=99.0% (LC-MS) |
| Total Impurities | <=1.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 148–152°C |
| Identification (NMR) | Consistent with structure |
| Heavy Metals | <=20 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 8-Bromo-[1,2,4]triazolo[1,5-a]pyridin-2-ylamine
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 8-Bromo-[1,2,4]triazolo[1,5-a]pyridin-2-ylamine
Safety Information of 8-Bromo-[1,2,4]triazolo[1,5-a]pyridin-2-ylamine
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 8-Bromo-[1,2,4]triazolo[1,5-a]pyridin-2-ylamine
Industrial 8-Bromo-[1,2,4]triazolo[1,5-a]pyridin-2-ylamine Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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