Ethyl 4-piperidinecarboxylate Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 1126-09-6 |
| Product name | Ethyl 4-piperidinecarboxylate |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for Ethyl 4-piperidinecarboxylate
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk Ethyl 4-piperidinecarboxylate Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of Ethyl 4-piperidinecarboxylate
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Synthesis of pharmaceutical intermediates | Used in the synthesis of piperidine derivatives |
| Agrochemicals | Preparation of agrochemical intermediates | Applied in the construction of heterocyclic compounds |
| Fine chemicals | Preparation of specialty chemicals | Employed as a functionalizing reagent in modification reactions |
| Organic synthesis | Construction of complex molecular frameworks | Involved in multistep organic synthesis reactions |
Manufacturing Quality Control of Ethyl 4-piperidinecarboxylate
| Test Item | Common Testing Methods | Method Overview |
|---|---|---|
| Appearance and Physical Properties | Visual Inspection and Physical Property Measurement | Observe sample color and state (typically colorless to pale yellow liquid or low-melting solid); determine melting point or boiling point range, conforming to pharmacopoeial or company specifications. |
| Purity (Main Component Content) | High-Performance Liquid Chromatography (HPLC) | Use C18 column with water-acetonitrile or methanol as mobile phase, UV detector (210–254 nm), quantification by external standard or internal standard method; typically requires ≥98.0%. |
| Organic Impurities (Impurity Profile) | HPLC or UPLC | Employ gradient elution to separate potential impurities such as unreacted starting materials (e.g., 4-piperidinecarboxylic acid), by-products (e.g., diester, decarboxylation products), etc.; total impurities generally controlled at ≤1.0%. |
| Residual Solvents | Gas Chromatography (GC) | Use DB-624 or HP-INNOWAX columns with FID detection; test according to ICH Q3C guidelines for residual solvents like ethanol, ether, toluene, ensuring compliance with specified limits. |
| Water Content | Karl Fischer Titration | Determine trace moisture using coulometric or volumetric Karl Fischer methods; control at ≤0.5% (more stringent requirements may apply if used in pharmaceutical active ingredient synthesis). |
| Melting Point / Boiling Point | Melting Point or Boiling Point Apparatus | Determine physical constants: the melting point of ethyl 4-piperidinecarboxylate is approximately 45–50°C (literature value), boiling point around 220–230°C, used for preliminary identification and supporting purity assessment. |
| Acidity/Alkalinity (pH) | pH Meter Measurement (in aqueous solution) | Dissolve sample in water or buffer solution and measure pH; typically required to be neutral (pH 6.0–8.0), assessing presence of acidic or basic impurities. |
| Heavy Metal Content | Atomic Absorption Spectroscopy (AAS) or ICP-MS | Determine lead, cadmium, mercury, arsenic, etc., according to pharmacopoeial methods (e.g., USP <231> or EP 2.4.8); limit controlled at ≤10 ppm, applicable to pharmaceutical-grade products. |
| Infrared Spectroscopy (IR) | Fourier Transform Infrared Spectroscopy (FT-IR) | Compare with reference spectrum to confirm characteristic functional groups such as ester carbonyl (C=O, ~1735 cm⁻¹) and piperidine ring (C-N, ~1250 cm⁻¹), used for structural confirmation. |
| Nuclear Magnetic Resonance (¹H NMR) | Proton Nuclear Magnetic Resonance Spectroscopy | Measure in CDCl₃ or DMSO-d₆; confirm structural signals such as ester protons (~4.1 ppm) and piperidine ring methylene protons (~2.5–3.0 ppm), used for structural verification of high-purity samples. |
| Specific Rotation (if applicable) | Polarimeter Measurement | Applicable only if chiral derivative or chiral center present (this compound is achiral); not typically applicable. For racemic mixtures or derivatives, specific rotation must be determined as required. |
Technical Specifications of Ethyl 4-piperidinecarboxylate
| Test Item | Specification |
|---|---|
| Appearance | Colorless to light yellow clear liquid |
| Purity | >=98.0% (GC) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Refractive Index (n20/D) | 1.465–1.475 |
| Relative Density (20°C/25°C) | 1.03–1.05 g/cm³ |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of Ethyl 4-piperidinecarboxylate
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of Ethyl 4-piperidinecarboxylate
Safety Information of Ethyl 4-piperidinecarboxylate
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of Ethyl 4-piperidinecarboxylate
Industrial Ethyl 4-piperidinecarboxylate Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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