2,4-DICHLORO-5,6,7,8-TETRAHYDROQUINAZOLINE Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 1127-85-1 |
| Product name | 2,4-DICHLORO-5,6,7,8-TETRAHYDROQUINAZOLINE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 2,4-DICHLORO-5,6,7,8-TETRAHYDROQUINAZOLINE
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 2,4-DICHLORO-5,6,7,8-TETRAHYDROQUINAZOLINE Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 2,4-DICHLORO-5,6,7,8-TETRAHYDROQUINAZOLINE
| Industry | Application | Process |
|---|---|---|
| Pesticides | Intermediate | Used in the synthesis of pesticide active ingredients |
| Pharmaceuticals | Intermediate | Used in the synthesis of pharmaceutical intermediates for subsequent drug manufacturing |
| Research | Chemical research | Serves as a building block in organic synthesis for investigating new chemical reactions and synthetic pathways |
Manufacturing Quality Control of 2,4-DICHLORO-5,6,7,8-TETRAHYDROQUINAZOLINE
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination based on peak area comparison against a certified reference standard using reversed-phase chromatography and UV detection at ~254 nm. |
| Related Substances | HPLC-UV or HPLC-MS | Separation and detection of structurally related impurities (e.g., mono-chloro analogs, hydrolysis/degradation products) using gradient elution and UV or mass-selective detection. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection to quantify volatile organic solvents (e.g., dichloromethane, toluene, methanol) per ICH Q3C guidelines. |
| Water Content | Karl Fischer Titration (Coulometric) | Electrochemical titration quantifying water via iodine generation and stoichiometric reaction with water in anhydrous medium. |
| Heavy Metals | ICP-MS | Multi-element trace metal quantification (e.g., Pb, Cd, Ni, Fe) after acid digestion, using isotopic detection with high sensitivity and low detection limits. |
| Chloride Content | Potentiometric Titration with AgNO₃ | Direct titration using silver nitrate; endpoint detected by silver ion-selective electrode based on formation of insoluble AgCl. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition measurement via controlled heating; onset and range indicate crystallinity and presence of impurities. |
| Residue on Ignition | Gravimetric Analysis | Determination of inorganic ash content after high-temperature incineration (700–800 °C) and weighing of residual residue. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry or wet dispersed sample using Mie scattering theory to determine volumetric particle size distribution. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light induced by chiral centers in solution, indicating enantiomeric purity if applicable. |
| pH of Aqueous Suspension | pH Meter | Electrochemical measurement of hydrogen ion activity in a standardized suspension (e.g., 1% w/v in water), reflecting acidic/basic impurities. |
| Organic Volatile Impurities (OVI) | GC-MS | Targeted and untargeted screening of genotoxic or highly volatile impurities using headspace or direct injection with mass spectral identification. |
| Microbiological Contamination | Membrane Filtration & Culture | Quantitative assessment of aerobic microorganisms and specified pathogens per pharmacopeial methods (e.g., USP <61>, <62>). |
Technical Specifications of 2,4-DICHLORO-5,6,7,8-TETRAHYDROQUINAZOLINE
| Test Item | Specification |
|---|---|
| Appearance | Off-white crystalline solid |
| Purity | >=98.0% (GC-MS) |
| Melting Point | 142–146 °C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Identification (NMR) | Conforms to reference spectrum |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 2,4-DICHLORO-5,6,7,8-TETRAHYDROQUINAZOLINE
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 2,4-DICHLORO-5,6,7,8-TETRAHYDROQUINAZOLINE
Safety Information of 2,4-DICHLORO-5,6,7,8-TETRAHYDROQUINAZOLINE
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 2,4-DICHLORO-5,6,7,8-TETRAHYDROQUINAZOLINE
Industrial 2,4-DICHLORO-5,6,7,8-TETRAHYDROQUINAZOLINE Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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