2,4,5-Trifluoro-3-methoxybenzoyl chloride Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 112811-66-2 |
| Product name | 2,4,5-Trifluoro-3-methoxybenzoyl chloride |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 2,4,5-Trifluoro-3-methoxybenzoyl chloride
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 2,4,5-Trifluoro-3-methoxybenzoyl chloride Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 2,4,5-Trifluoro-3-methoxybenzoyl chloride
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Key intermediate for synthesizing quinolone antibacterial agents (e.g., gatifloxacin, pazufloxacin) | Acylation and condensation reactions to construct the quinolone core structure |
| Agrochemical Intermediates | Fluorinated aromatic building block for synthesizing novel fluorinated agrochemicals | Nucleophilic substitution or coupling reactions to introduce the trifluoroethoxybenzoyl group |
| Organic Synthesis | Custom molecule synthesis incorporating fluorinated aromatic acyl structures | Typical acid chloride reactions with amines, alcohols, or phenols to yield amides or ester derivatives |
Manufacturing Quality Control of 2,4,5-Trifluoro-3-methoxybenzoyl chloride
| Detection Item | Common Testing Methods | Method Overview |
|---|---|---|
| Appearance | Visual Inspection | Observe the sample under natural light or standard illumination for color (typically colorless to pale yellow liquid), physical state, and check for turbidity, precipitates, or foreign particles. |
| Purity | Gas Chromatography (GC) or High-Performance Liquid Chromatography (HPLC) | Separate and analyze the sample using GC or HPLC. Calculate the main component content by area normalization or external standard method to assess purity (typically requiring ≥98.0%). |
| Water Content | Karl Fischer Titration | Determine water content quantitatively by reacting with Karl Fischer reagent via potentiometric or coulometric titration, ensuring it remains within specified limits (e.g., ≤0.1%). |
| Acid Value / Free Acid | Acid-Base Titration | Dissolve the sample in an appropriate solvent (e.g., ethanol), use phenolphthalein as indicator, and titrate with standardized sodium hydroxide solution to calculate free acid content (e.g., 3-methoxy-2,4,5-trifluorobenzoic acid). |
| Residual Solvents | Headspace Gas Chromatography (HS-GC) | Use headspace injection combined with GC-FID detection to qualitatively and quantitatively analyze organic solvents (e.g., dichloromethane, toluene) potentially remaining from manufacturing processes, complying with ICH Q3C guidelines. |
| Melting Point / Boiling Point | Melting Point or Boiling Point Apparatus | Determine physical constants for identification purposes; 2,4,5-trifluoro-3-methoxybenzoyl chloride is a liquid, typically boiling point is measured under atmospheric or reduced pressure and compared with literature values. |
| Structural Confirmation | Nuclear Magnetic Resonance (NMR), Infrared Spectroscopy (IR), Mass Spectrometry (MS) | Confirm molecular structure using ¹H NMR, ¹³C NMR, FT-IR, and MS to verify the presence and correctness of functional groups (e.g., acyl chloride, methoxy group, fluorinated benzene ring). |
| Heavy Metals | Atomic Absorption Spectroscopy (AAS) or Inductively Coupled Plasma Mass Spectrometry (ICP-MS) | Process samples according to pharmacopoeial methods and determine total levels of heavy metals such as lead, arsenic, cadmium, and mercury, ensuring compliance with safety limits (e.g., ≤20 ppm). |
Technical Specifications of 2,4,5-Trifluoro-3-methoxybenzoyl chloride
| Test Item | Specification |
|---|---|
| Appearance | White to light yellow crystalline powder |
| Purity | >=98.0% (GC-MS) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Melting Point | 68–72°C |
| Identification (NMR) | Consistent with structure |
| Identification (IR) | Consistent with structure |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 2,4,5-Trifluoro-3-methoxybenzoyl chloride
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 2,4,5-Trifluoro-3-methoxybenzoyl chloride
Safety Information of 2,4,5-Trifluoro-3-methoxybenzoyl chloride
| Pictograms |  |
| Signal Word | Danger |
| Safety Data Sheet | |
Packaging of 2,4,5-Trifluoro-3-methoxybenzoyl chloride
Industrial 2,4,5-Trifluoro-3-methoxybenzoyl chloride Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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