China Factory Direct
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| CAS number | 112883-29-1 |
| Product name | FMOC-D-TYR-OH |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeMaterial GradeSpecialty GradeReagent Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Biopharmaceuticals | Intermediate for peptide synthesis | Used in solid-phase peptide synthesis (SPPS) as a protected amino acid; the tyrosine amino group is protected with an Fmoc group to enable selective coupling |
| Chemical Research | Synthesis of fluorescently labeled peptides | The phenolic hydroxyl group on the tyrosine side chain is modified to conjugate fluorescent probes or functional molecules for applications in bioimaging and protein interaction studies |
| Pharmaceutical Development | Design of anticancer agents and targeted therapeutics | Serves as a key building block for structurally defined peptide drugs, incorporated into targeted delivery systems or enzyme inhibitor designs |
| Advanced Materials | Synthesis of functionalized biomaterials | Applied in the preparation of bioactive hydrogels or nanocarriers, leveraging tyrosine’s reactivity for crosslinking or surface functionalization |
| Molecular Diagnostics | Diagnostic reagent development | Used to synthesize peptide probes that specifically recognize antibodies or targets, supporting the construction of assays for disease biomarker detection |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification by comparison of peak area against a certified reference standard using reversed-phase chromatography and UV detection at 265 nm. |
| Related Substances | HPLC-UV | Separation and quantification of impurities (e.g., FMOC-D-Tyr-OH diastereomers, des-FMOC derivative, residual solvents) using gradient HPLC with UV detection. |
| Chiral Purity | Chiral HPLC | Enantioselective separation on a chiral stationary phase to determine D/L ratio; D-isomer content confirmed by retention time match and peak purity. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration with iodine-based reagent to quantify water based on stoichiometric electrochemical reaction. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection to quantify common solvents (e.g., DMF, DCM, methanol) per ICH Q3C guidelines. |
| Heavy Metals | ICP-MS | Multi-element trace metal quantification (e.g., Pb, Cd, Hg, As) after acid digestion using inductively coupled plasma mass spectrometry. |
| Appearance | Visual Inspection | Assessment of physical state, color, and clarity of solid sample against established reference standards under controlled lighting. |
| Melting Point | Capillary Melting Point Apparatus | Determination of temperature range over which the crystalline solid transitions to liquid, indicating purity and identity. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light at 589 nm to confirm chiral integrity and concentration-corrected specific rotation value. |
| Loss on Drying | Gravimetric Analysis | Weight loss measured after drying under specified vacuum and temperature conditions to determine volatile content including moisture and residual solvents. |
| Residue on Ignition | Sulfated Ash Test | Quantification of non-volatile inorganic residue after high-temperature ignition following sulfuric acid treatment. |
| pH of Solution | pH Meter | Measurement of hydrogen ion activity in a defined aqueous or aqueous-methanolic solution using calibrated glass electrode. |
| Test Item | Specification |
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| Appearance | White solid |
| Purity | >=98.0% (by LC-MS) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Optical Rotation | +19.5° to +20.5° (c=1, in 1M HCl) |
| Melting Point | 148°C to 152°C |
| Identification (NMR) | Consistent with structure |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.