Fmoc-D-Aspartic acid beta-tert-butyl ester Bulk Supply for Industrial Use
China Factory Direct
 |
|
| CAS number | 112883-39-3 |
| Product name | Fmoc-D-Aspartic acid beta-tert-butyl ester |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
QUOTE TYPE
PACKAGING TYPE
TOTAL QUANTITY(KG)
PREFERRED SHIPPING METHOD
YOUR COMPANY
YOUR E-MAIL
Calculate Summary
Based on current marketvolatility and material availability.
Documents We Provide for Fmoc-D-Aspartic acid beta-tert-butyl ester
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk Fmoc-D-Aspartic acid beta-tert-butyl ester Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of Fmoc-D-Aspartic acid beta-tert-butyl ester
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate in peptide drug synthesis for introducing aspartic acid residues | Fmoc-based solid-phase peptide synthesis (SPPS) |
| Biochemistry | Research on proteins and peptides, serving as a building block for constructing specific sequences | Liquid-phase peptide synthesis for laboratory-scale preparation |
| Pharmaceutical R&D | Preparation of biologically active aspartic acid derivatives or analogues | Use as a protected amino acid building block in organic synthesis |
Manufacturing Quality Control of Fmoc-D-Aspartic acid beta-tert-butyl ester
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reversed-phase HPLC with UV detection at 260–280 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of structurally related impurities (e.g., Fmoc-Asp-OtBu diastereomers, deprotection by-products) using gradient RP-HPLC. |
| Residual Solvents | GC-FID | Identification and quantification of volatile organic solvents (e.g., DMF, DCM, MTBE) by gas chromatography with flame ionization detection. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration measuring water via iodine-sulfur dioxide reaction in pyridine/methanol medium. |
| Residual Metals (e.g., Pd, Ni, Cu) | ICP-MS | Multi-element trace metal quantification after acid digestion, leveraging high sensitivity and isotopic resolution. |
| Optical Purity (Enantiomeric Excess) | Chiral HPLC | Separation of D- and L-enantiomers on a chiral stationary phase (e.g., cellulose-based), with UV detection and ee calculation from peak areas. |
| Residual Chloride | Ion Chromatography (IC) | Quantification of chloride ions using suppressed conductivity detection after anion exchange separation. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition measurement via controlled heating; sharp melting range indicates crystallinity and absence of significant impurities. |
| Appearance | Visual Inspection | Assessment of physical state, color, and homogeneity under controlled lighting against defined standards (e.g., white to off-white crystalline powder). |
| Loss on Drying (LOD) | Gravimetric Thermobalance | Mass loss upon heating under specified temperature/vacuum conditions, reflecting volatile content including residual solvents and moisture. |
| Specific Optical Rotation | [α]D | Measurement of plane-polarized light rotation in solution at 589 nm; confirms chiral integrity and batch-to-batch consistency. |
| Residual TFA | GC-MS | Targeted quantification of trifluoroacetic acid using gas chromatography coupled with mass spectrometric detection for selectivity and sensitivity. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry powder particle size distribution based on Mie scattering theory, relevant for filtration and formulation performance. |
| Microbial Limits | Membrane Filtration + Culture | Enumeration of aerobic microorganisms and detection of specified pathogens per pharmacopeial methods (e.g., USP <61>). |
Technical Specifications of Fmoc-D-Aspartic acid beta-tert-butyl ester
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% (LC-MS) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Optical Rotation | +22.0 to +27.0 deg (c=1, DMF) |
| Melting Point | 128 to 132 °C |
| Identification (NMR) | Conforms to reference spectrum |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
|
|
Download COA of Fmoc-D-Aspartic acid beta-tert-butyl ester
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of Fmoc-D-Aspartic acid beta-tert-butyl ester
Safety Information of Fmoc-D-Aspartic acid beta-tert-butyl ester
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of Fmoc-D-Aspartic acid beta-tert-butyl ester
Industrial Fmoc-D-Aspartic acid beta-tert-butyl ester Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
Use Bulk
Supply Factory
Direct ISO 9001
Certified Samples
Available Stable
Supply