FMOC-D-NLE-OH Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 112883-41-7 |
| Product name | FMOC-D-NLE-OH |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for FMOC-D-NLE-OH
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk FMOC-D-NLE-OH Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of FMOC-D-NLE-OH
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Synthesis | As an amino acid protecting group for Fmoc protection of D-norleucine in peptide synthesis | Preparation of Fmoc-D-norleucine via reaction of Fmoc-Cl with D-norleucine for use in solid-phase peptide synthesis (SPPS), followed by stepwise coupling to assemble the peptide chain |
| Biochemical Research | Synthesis of D-norleucine-containing peptides for structure–activity relationship studies | Use of Fmoc-protected D-norleucine as an amino acid derivative coupled to resin in automated peptide synthesizers, followed by iterative deprotection and coupling cycles to construct sequence-defined peptides |
| Pharmaceutical Manufacturing | Synthesis of bioactive peptide therapeutics, such as antimicrobial peptides or hormone analogs | Utilization of Fmoc-D-norleucine as a key intermediate in multi-step solid-phase or solution-phase peptide synthesis under GMP conditions |
Manufacturing Quality Control of FMOC-D-NLE-OH
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification by comparison of peak area against a certified reference standard using UV detection at 260-280 nm. |
| Chiral Purity | Chiral HPLC | Enantiomeric separation on a chiral stationary phase with UV detection; D-isomer content determined relative to L-isomer peak. |
| Water Content | Karl Fischer Titration | Electrochemical titration using iodine generated in situ to react stoichiometrically with water. |
| Residual Solvents | GC-FID | Separation and quantification of volatile organic solvents by gas chromatography with flame ionization detection. |
| Heavy Metals | ICP-MS | Multi-element trace metal quantification based on mass-to-charge ratio detection after acid digestion. |
| Residual Chloride | Ion Chromatography | Anion separation on a high-capacity column with suppressed conductivity detection. |
| Specific Optical Rotation | [a]D Measurement | Measurement of rotation angle of plane-polarized light at 589 nm, indicating chiral integrity and concentration. |
| Loss on Drying | Gravimetric Analysis | Mass loss measured after drying under controlled temperature and vacuum conditions. |
| Appearance | Visual Inspection | Assessment of physical state, color, and presence of foreign particles under standardized lighting. |
| pH of Solution | Potentiometric Titration | Measurement of hydrogen ion activity in aqueous suspension using calibrated pH electrode. |
| Related Substances | HPLC-UV | Detection and quantification of structurally related impurities using gradient elution and UV detection. |
| Microbial Contamination | Membrane Filtration | Enumeration of aerobic microorganisms via filtration, membrane transfer to culture medium, and colony counting. |
Technical Specifications of FMOC-D-NLE-OH
| Test Item | Specification |
|---|---|
| Appearance | Off-white solid |
| Purity | >=98.0% (LC-MS) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Melting Point | 132–136°C |
| Optical Rotation | +17.0 to +19.0° (c=1, DMF) |
| Identification (NMR) | Conforms to reference spectrum |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of FMOC-D-NLE-OH
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of FMOC-D-NLE-OH
Packaging of FMOC-D-NLE-OH
Industrial FMOC-D-NLE-OH Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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