4-BROMO-3-FLUOROBENZOIC ACID ETHYL ESTER Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 1130165-74-0 |
| Product name | 4-BROMO-3-FLUOROBENZOIC ACID ETHYL ESTER |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 4-BROMO-3-FLUOROBENZOIC ACID ETHYL ESTER
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 4-BROMO-3-FLUOROBENZOIC ACID ETHYL ESTER Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 4-BROMO-3-FLUOROBENZOIC ACID ETHYL ESTER
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Used in the synthesis of active pharmaceutical ingredients (APIs), including antitumor agents and kinase inhibitors | Serves as an aromatic ring substituent modification building block, incorporated into target molecular scaffolds via reactions such as Suzuki coupling, Buchwald-Hartwig amination, or ester hydrolysis/amidation |
| Pesticide R&D | Structural unit for novel fluorinated insecticides and herbicides | Participates in heterocycle construction or side-chain functionalization—for example, cyclization with hydrazide compounds to prepare triazole derivatives |
| Organic Synthesis | Highly selective fluorine/bromine bifunctional synthon for multistep sequential transformations | The bromine atom enables metallation (e.g., with Mg or Zn) or cross-coupling reactions, while the fluorine atom modulates reactivity and metabolic stability through electronic effects |
Manufacturing Quality Control of 4-BROMO-3-FLUOROBENZOIC ACID ETHYL ESTER
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification by peak area comparison against a certified reference standard using reversed-phase chromatography and UV detection at 220-254 nm. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC with UV detection; identification based on retention time matching and threshold limits per ICH Q3B. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection to quantify volatile organic solvents (e.g., ethanol, ethyl acetate) against calibrated standards. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to determine trace water content via stoichiometric reaction. |
| Heavy Metals | ICP-MS | Quantitative determination of elemental impurities (e.g., Pb, Cd, Ni) after acid digestion, using inductively coupled plasma mass spectrometry for sub-ppb sensitivity. |
| Chloride Impurity | Ion Chromatography | Separation and quantification of chloride ions using suppressed conductivity detection after aqueous extraction. |
| Residue on Ignition | Gravimetric Analysis | Measurement of non-volatile inorganic residue after high-temperature ashing at 700-800 C and weighing. |
| Melting Point | Capillary Melting Point Apparatus | Determination of solid-to-liquid phase transition temperature range using controlled heating and visual observation. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light induced by chiral molecules in solution at specified concentration and wavelength (e.g., 589 nm). |
| Acid Value | Acid-Base Titration | Neutralization of free carboxylic acid groups with standardized NaOH solution using phenolphthalein indicator or potentiometric endpoint detection. |
| Appearance | Visual Inspection | Assessment of physical state, color, and clarity against established reference standards under controlled lighting conditions. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry or dispersed sample using light scattering pattern to derive volume-based particle size distribution. |
Technical Specifications of 4-BROMO-3-FLUOROBENZOIC ACID ETHYL ESTER
| Test Item | Specification |
|---|---|
| Appearance | Colorless to pale yellow liquid |
| Purity | >=98.0% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Refractive Index (n20/D) | 1.540–1.550 |
| Relative Density (20°C/25°C) | 1.38–1.42 g/cm³ |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 4-BROMO-3-FLUOROBENZOIC ACID ETHYL ESTER
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 4-BROMO-3-FLUOROBENZOIC ACID ETHYL ESTER
Safety Information of 4-BROMO-3-FLUOROBENZOIC ACID ETHYL ESTER
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 4-BROMO-3-FLUOROBENZOIC ACID ETHYL ESTER
Industrial 4-BROMO-3-FLUOROBENZOIC ACID ETHYL ESTER Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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