2,6-DICHLORO-5-FLUORONICOTINAMIDE Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 113237-20-0 |
| Product name | 2,6-DICHLORO-5-FLUORONICOTINAMIDE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 2,6-DICHLORO-5-FLUORONICOTINAMIDE
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 2,6-DICHLORO-5-FLUORONICOTINAMIDE Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 2,6-DICHLORO-5-FLUORONICOTINAMIDE
| Industry | Application | Process |
|---|---|---|
| Pesticides | Novel insecticide intermediate for synthesizing neonicotinoid insecticides such as flupyradifurone | Used to construct the key pyridine amide structure via nucleophilic substitution and cyclization with reagents such as 3-hydroxypropionitrile |
| Pharmaceuticals | Potential pharmaceutical intermediate for developing kinase inhibitor-based anticancer compounds | Applied in Suzuki coupling, amination, or reductive amination to build fluorinated heterocyclic pharmacophores |
Manufacturing Quality Control of 2,6-DICHLORO-5-FLUORONICOTINAMIDE
| Test Item | Common Testing Methods | Method Overview |
|---|---|---|
| Appearance | Visual Inspection | Observe the sample's color, physical state, and presence of visible impurities under natural light or standard lighting conditions. |
| Content Assay | High-Performance Liquid Chromatography (HPLC) | Utilize a reversed-phase column (e.g., C18) with an aqueous/organic solvent (e.g., acetonitrile or methanol) mobile phase and a UV detector to measure the peak area of the target compound; calculate content using external standard or internal standard methods. |
| Related Substances (Impurity Analysis) | High-Performance Liquid Chromatography (HPLC) | Optimize gradient elution conditions to separate the main component from potential synthetic intermediates, degradation products, and other impurities; evaluate impurity levels via peak area normalization or reference standard methods. |
| Fluorine Content | Ion Chromatography (IC) or Oxygen Bomb Combustion-Ion Chromatography | Decompose the sample via oxygen bomb combustion to release fluoride ions, absorb them in water, and quantify fluoride ion concentration using ion chromatography to verify the presence and content of fluorine in the molecule. |
| Chlorine Content | Oxygen Bomb Combustion-Silver Titration or Ion Chromatography | Combust the sample in an oxygen stream to convert chlorine to chloride ions; quantify chloride ions in the absorption solution via silver nitrate titration (silver titration method) or ion chromatography. |
| Water Content | Karl Fischer Titration | Utilize the reaction of iodine and sulfur dioxide with water in an anhydrous environment to precisely determine water content via coulometric titration. |
| Residual Solvents | Gas Chromatography (GC) | According to ICH guidelines, use headspace injection-gas chromatography to detect organic solvents potentially residual from manufacturing processes (e.g., methanol, ethanol, dichloromethane). |
| Melting Point | Capillary Melting Point Determination or Automatic Melting Point Apparatus | Load the sample into a capillary tube and slowly heat it on a melting point apparatus; observe the initial and complete melting temperatures to assess purity and material characteristics. |
| Infrared Spectroscopy (IR) | Fourier Transform Infrared Spectroscopy (FT-IR) | Acquire the sample’s infrared spectrum via pellet method or ATR accessory and compare it with a reference spectrum to confirm the presence of functional groups (e.g., amide, C-F, C-Cl). |
| Nuclear Magnetic Resonance (NMR) | ¹H-NMR and ¹⁹F-NMR | Dissolve the sample in a deuterated solvent and analyze molecular structure using proton and fluorine spectra to verify substituent positions and detect impurities through residual signal identification. |
| Thermal Stability | Differential Scanning Calorimetry (DSC) | Measure the sample’s endothermic or exothermic behavior during heating to evaluate melting temperature, polymorphic transitions, or decomposition temperature, reflecting thermal stability. |
| Polymorph Analysis | X-ray Powder Diffraction (XRD) | Analyze characteristic diffraction peaks of solid samples to identify different polymorphic forms and ensure batch-to-batch consistency (where applicable). |
Technical Specifications of 2,6-DICHLORO-5-FLUORONICOTINAMIDE
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow solid |
| Purity | >=98.0% (HPLC) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 142–146°C |
| Identification (NMR) | Consistent with structure |
| Heavy Metals | <=20 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 2,6-DICHLORO-5-FLUORONICOTINAMIDE
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 2,6-DICHLORO-5-FLUORONICOTINAMIDE
Safety Information of 2,6-DICHLORO-5-FLUORONICOTINAMIDE
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 2,6-DICHLORO-5-FLUORONICOTINAMIDE
Industrial 2,6-DICHLORO-5-FLUORONICOTINAMIDE Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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