China Factory Direct
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| CAS number | 1136-86-3 |
| Product name | 3',4',5'-TRIMETHOXYACETOPHENONE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Chemicals | Synthetic intermediate for the anti-asthmatic drug ligustrazine (tetramethylpyrazine) | Serves as the starting material in the synthesis of tetramethylpyrazine (ligustrazine) via reduction, bromination, and amination steps |
| Pharmaceutical Chemicals | Organic synthetic intermediate for bioactive molecules containing polymethoxybenzene motifs | Functions as an aryl ketone building block; side chains are introduced via Clemmensen reduction, Huang-Minlon reduction, or Grignard reactions to construct complex pharmaceutical scaffolds |
| Scientific Research | Photochemical reaction and mechanistic studies | Employed in photoinduced radical reactions or cycloadditions owing to its specific conjugated structure |
| Chemical Trading | Reference standard | Used for qualitative identification and quantitative analysis in gas chromatography (GC) or high-performance liquid chromatography (HPLC) |
| Test Item | Common Testing Method | Method Overview |
|---|---|---|
| Appearance | Visual Inspection | Observe the color, physical state, and presence of visible impurities. Typically appears as a white to off-white crystalline powder. |
| Melting Point | Melting Point Determination (Capillary Method) | Determine the melting temperature range using a melting point apparatus; compare with reference value (literature value approximately 78–80°C) to assess purity. |
| Assay | High-Performance Liquid Chromatography (HPLC) | Use a reversed-phase C18 column and UV detector (e.g., 254 nm); determine active ingredient content via external standard method or area normalization method to evaluate purity. |
| Related Substances (Impurities) | High-Performance Liquid Chromatography (HPLC) | Separate and detect potential impurities such as synthesis intermediates, by-products, or degradation products under gradient or isocratic elution conditions; calculate total impurity levels. |
| Loss on Drying | Thermogravimetric Analysis (TGA) or Oven Drying Method | Dry the sample at 105°C for a specified time (e.g., 2 hours) and measure the percentage weight loss to assess moisture and volatile impurity content. |
| Sulfated Ash (Residue on Ignition) | Residue on Ignition Test | Iignite the sample at high temperature (approximately 600–800°C), then weigh the residual inorganic matter to evaluate inorganic impurity content. |
| Heavy Metals | Atomic Absorption Spectroscopy (AAS) or ICP-MS | After sample digestion, measure residual levels of heavy metal elements such as lead, cadmium, mercury, and arsenic to ensure compliance with pharmacopoeial limits. |
| Solubility | Solubility Test | Test solubility in various solvents such as water, ethanol, methanol, and acetone; used for identification support and process evaluation. |
| Structural Confirmation | Fourier Transform Infrared Spectroscopy (FT-IR) | Obtain the infrared absorption spectrum and compare it with a reference spectrum to confirm the presence of functional groups (e.g., carbonyl, methoxy). |
| Structural Confirmation | Nuclear Magnetic Resonance Spectroscopy (NMR) | Analyze molecular structure consistency using ¹H-NMR and ¹³C-NMR to verify hydrogen and carbon spectra against the target compound. |
| Polymorphic Form Analysis | X-Ray Diffraction (XRD) | Analyze crystal structure characteristics for polymorphism studies or batch-to-batch consistency control (if applicable). |
| Test Item | Specification |
|---|---|
| Appearance | Off-white crystalline solid |
| Purity | >=98.0% (GC-MS) |
| Melting Point | 78–82°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Identification (NMR) | Conforms to reference spectrum |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.