2-Amino-3-bromobenzonitrile Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 114344-60-4 |
| Product name | 2-Amino-3-bromobenzonitrile |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 2-Amino-3-bromobenzonitrile
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 2-Amino-3-bromobenzonitrile Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 2-Amino-3-bromobenzonitrile
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Chemicals | Pharmaceutical Intermediates | Used in constructing core scaffolds of targeted therapeutic molecules, including protein kinase inhibitors (e.g., JAK inhibitors) and RET tyrosine kinase inhibitors. |
| Agrochemicals | Agrochemical Intermediates | Applied in heterocyclic structural modification for synthesizing benzoylurea-based insect growth regulators and other novel insecticides. |
| Organic Synthesis | Functional Material Intermediates | Participates in coupling reactions—including Suzuki and Buchwald–Hartwig couplings—to construct conjugated organic molecular frameworks, leveraging differential reactivity of the amino and bromo groups. |
| Research Reagents | Chemical Reagents | Serves as a building block for constructing specially substituted benzene ring structures, supporting new compound screening and laboratory-scale synthesis. |
Manufacturing Quality Control of 2-Amino-3-bromobenzonitrile
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification by comparison of peak area against a certified reference standard using reversed-phase chromatography and UV detection at 254 nm. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC with UV detection; identification based on retention time matching and threshold limits per ICH Q3A. |
| Residual Solvents | GC-FID | Detection and quantification of volatile organic solvents (e.g., toluene, acetonitrile) using gas chromatography with flame ionization detection and internal standard calibration. |
| Water Content | Karl Fischer Titration | Volumetric titration using iodine, sulfur dioxide, and pyridine in methanol; based on stoichiometric reaction with water. |
| Heavy Metals | ICP-OES | Multi-element determination of Pb, Cd, Hg, As, and others after acid digestion; quantification via atomic emission intensity at characteristic wavelengths. |
| Chloride Impurity | Ion Chromatography | Separation and quantification of chloride ions using anion-exchange column and suppressed conductivity detection. |
| Residue on Ignition | Gravimetric Analysis | Measurement of non-volatile inorganic residue after incineration at 700-800 C and subsequent weighing. |
| Melting Point | Capillary Melting Point Apparatus | Determination of temperature range at which solid transitions to liquid, observed visually under controlled heating rate. |
| Appearance | Visual Inspection | Assessment of physical state, color, and clarity of sample against specified criteria (e.g., white to off-white crystalline powder). |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light induced by chiral molecules in solution; used to confirm enantiomeric identity and absence of racemization. |
| Particle Size Distribution | Laser Diffraction | Analysis of particle size distribution based on angular variation of laser light scattering from dispersed particles in air or liquid medium. |
| pH of Aqueous Suspension | pH Meter | Measurement of hydrogen ion activity in a defined suspension (e.g., 1% w/v in water) using calibrated glass electrode and reference electrode. |
Technical Specifications of 2-Amino-3-bromobenzonitrile
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow solid |
| Purity | >=98.0% (GC-MS) |
| Melting Point | 75–79 °C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 2-Amino-3-bromobenzonitrile
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 2-Amino-3-bromobenzonitrile
Packaging of 2-Amino-3-bromobenzonitrile
Industrial 2-Amino-3-bromobenzonitrile Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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