Fmoc-D-leucine Bulk Supply for Industrial Use
China Factory Direct
 |
|
| CAS number | 114360-54-2 |
| Product name | Fmoc-D-leucine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeMaterial GradeSpecialty GradeReagent Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
QUOTE TYPE
PACKAGING TYPE
TOTAL QUANTITY(KG)
PREFERRED SHIPPING METHOD
YOUR COMPANY
YOUR E-MAIL
Calculate Summary
Based on current marketvolatility and material availability.
Documents We Provide for Fmoc-D-leucine
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk Fmoc-D-leucine Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of Fmoc-D-leucine
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Synthesis | Intermediate in the synthesis of peptide-based drugs | Used in solid-phase peptide synthesis (SPPS) |
| Biopharmaceuticals | Preparation of targeted therapeutics and biologics | Applied in liquid-phase peptide synthesis |
| Chemical Reagents | Amino acid derivatization reagent for analytical chemistry | Fmoc protecting group introduction and removal |
| Materials Science | Synthesis of functional peptide materials | Employed in molecular self-assembly techniques |
| Research | Protein structure and function studies | Biomacromolecule synthesis and modification |
Manufacturing Quality Control of Fmoc-D-leucine
| Test Item | Common Testing Methods | Method Overview |
|---|---|---|
| Appearance | Visual Inspection | Observe the sample's color, physical state (e.g., white to off-white crystalline powder), and presence of foreign matter with the naked eye to determine compliance with appearance requirements. |
| Identification | Infrared Spectroscopy (IR) High-Performance Liquid Chromatography (HPLC) Mass Spectrometry (MS) |
- IR: Measure the infrared absorption spectrum and compare with reference spectra to confirm structural characteristics. - HPLC: Confirm identity by comparing retention time with a reference standard under specified chromatographic conditions. - MS: Confirm molecular weight and structure through molecular ion and fragment ion peaks. |
| Assay | High-Performance Liquid Chromatography (HPLC) | Use a reversed-phase C18 column with an appropriate mobile phase (e.g., acetonitrile-water system containing ion-pair reagents such as trifluoroacetic acid) under isocratic or gradient elution. Detection is performed using a UV detector (typically at 210 nm or 220 nm), and the content of Fmoc-D-leucine is calculated using the external standard method. |
| Related Substances (Impurities) | High-Performance Liquid Chromatography (HPLC) | Apply a high-resolution reversed-phase HPLC method to detect and quantify possible impurities such as Fmoc-D-leucine isomers (L-form), deprotected products (D-leucine), Fmoc-OH, and synthetic by-products. Area normalization or main component self-reference methods are typically used. |
| Specific Optical Rotation | Polarimetry | Prepare a solution of defined concentration (e.g., 1% w/v, commonly in DMF or methanol), measure optical rotation at a specified temperature and wavelength (usually the sodium D-line, 589 nm), and calculate specific optical rotation to verify D-configuration purity. |
| Water Content | Karl Fischer Titration | Determine the water content accurately using volumetric or coulometric Karl Fischer titration to control mass variation caused by hygroscopicity. |
| Residual Solvents | Gas Chromatography (GC) | Based on ICH Q3C guidelines, analyze residual organic solvents (e.g., dichloromethane, DMF, ethanol, diethyl ether) possibly present from synthesis or purification using headspace or direct injection GC methods. |
| Melting Point | Capillary Melting Point Method | Determine the melting temperature range of the sample using a melting point apparatus, serving as an auxiliary indicator of purity and crystal form. |
| pH Value (if applicable) | pH Meter Method | If the sample is used in solution for specific applications, measure the pH in water or a specified solvent to assess the influence of acidic or basic impurities. |
Technical Specifications of Fmoc-D-leucine
| Test Item | Specification |
|---|---|
| Appearance | Off-white solid |
| Purity | >=98.0% (LC-MS) |
| Optical Rotation | +22.0 to +28.0 deg (c=1, DMF) |
| Melting Point | 75.0 to 79.0 °C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
|
|
Download COA of Fmoc-D-leucine
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of Fmoc-D-leucine
Packaging of Fmoc-D-leucine
Industrial Fmoc-D-leucine Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
Use Bulk
Supply Factory
Direct ISO 9001
Certified Samples
Available Stable
Supply