(S)-3-PHENYL-2-[(PYRAZIN-2-YLCARBONYL)AMINO] PROPANOIC ACID Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 114457-94-2 |
| Product name | (S)-3-PHENYL-2-[(PYRAZIN-2-YLCARBONYL)AMINO] PROPANOIC ACID |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for (S)-3-PHENYL-2-[(PYRAZIN-2-YLCARBONYL)AMINO] PROPANOIC ACID
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk (S)-3-PHENYL-2-[(PYRAZIN-2-YLCARBONYL)AMINO] PROPANOIC ACID Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of (S)-3-PHENYL-2-[(PYRAZIN-2-YLCARBONYL)AMINO] PROPANOIC ACID
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Key intermediate in the synthesis of the anticancer drug bortezomib | Used as a raw material in multi-step chemical synthesis to construct the molecular framework of bortezomib |
| Pharmaceuticals | Preparation of boronic acid-based proteasome inhibitors | Applied in coupling reactions to introduce the boronic acid moiety, yielding pharmacologically active final products |
Manufacturing Quality Control of (S)-3-PHENYL-2-[(PYRAZIN-2-YLCARBONYL)AMINO] PROPANOIC ACID
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 210 nm, comparing peak area to a certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities by gradient HPLC-UV against qualified reference standards or threshold-based reporting. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify common organic solvents based on calibrated external standards. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to determine water content via electrochemical reaction stoichiometry. |
| Heavy Metals | ICP-MS | Multi-element trace metal quantification by inductively coupled plasma mass spectrometry after acid digestion and dilution. |
| Chloride Impurity | Ion Chromatography | Separation and quantification of chloride ions using suppressed conductivity detection with carbonate/bicarbonate eluent. |
| Optical Rotation | [a]D Measurement | Determination of specific optical rotation using a polarimeter at 20 C and sodium D-line (589 nm) to confirm chiral integrity. |
| Residual Palladium | ICP-OES | Quantification of palladium catalyst residue after microwave-assisted acid digestion using inductively coupled plasma optical emission spectroscopy. |
| Particle Size Distribution | Laser Diffraction | Measurement of dry or wet dispersed particle size distribution based on Mie scattering theory. |
| pH of Aqueous Suspension | Potentiometric pH Measurement | Direct measurement of pH in a defined aqueous suspension using a calibrated glass electrode system. |
| Melting Point | Capillary Melting Point Apparatus | Thermal determination of onset and range of solid-to-liquid transition using controlled heating and visual observation. |
| Microbial Limits | Membrane Filtration and Plate Count | Enumeration of aerobic microorganisms via membrane filtration followed by incubation on soybean-casein digest agar. |
Technical Specifications of (S)-3-PHENYL-2-[(PYRAZIN-2-YLCARBONYL)AMINO] PROPANOIC ACID
| Test Item | Specification |
|---|---|
| Appearance | Off-white solid |
| Purity | >=98.0% (LC-MS) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Optical Rotation | +12.0 to +14.0° (c=1, in methanol) |
| Melting Point | 138 to 142°C |
| Identification (NMR) | Conforms to reference spectrum |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of (S)-3-PHENYL-2-[(PYRAZIN-2-YLCARBONYL)AMINO] PROPANOIC ACID
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of (S)-3-PHENYL-2-[(PYRAZIN-2-YLCARBONYL)AMINO] PROPANOIC ACID
Safety Information of (S)-3-PHENYL-2-[(PYRAZIN-2-YLCARBONYL)AMINO] PROPANOIC ACID
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of (S)-3-PHENYL-2-[(PYRAZIN-2-YLCARBONYL)AMINO] PROPANOIC ACID
Industrial (S)-3-PHENYL-2-[(PYRAZIN-2-YLCARBONYL)AMINO] PROPANOIC ACID Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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