China Factory Direct
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| CAS number | 114676-59-4 |
| Product name | D-Proline, 4-hydroxy-, methyl ester, hydrochloride (1:1), (4R)- |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Pharmaceutical intermediates (e.g., for synthesis of Parkinson’s disease medications) | Used in organic synthesis |
| Chemicals | Chiral building blocks | Applied in asymmetric synthesis |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reverse-phase HPLC with UV detection at 210 nm, relative to a certified reference standard. |
| Chiral Purity | (R,R)-Enantiomeric Excess | Chiral HPLC with chiral stationary phase (e.g., Chirobiotic T) and UV detection; separates (2R,4R) from other stereoisomers. |
| Related Substances | HPLC-UV | Detects and quantifies structurally related impurities (e.g., diastereomers, hydrolysis products) using gradient HPLC-UV. |
| Residual Solvents | GC-FID | Quantifies residual methanol, ethyl acetate, or dichloromethane by gas chromatography with flame ionization detection. |
| Water Content | Karl Fischer Titration | Measures trace water via coulometric or volumetric titration using iodine-based redox reaction in anhydrous methanol medium. |
| Heavy Metals | ICP-OES | Determines total heavy metal content (Pb, Cd, Ni, Cu, Fe) after acid digestion by optical emission spectroscopy. |
| Chloride Content | Potentiometric Titration | Quantifies chloride ions using silver nitrate titrant with silver/silver chloride indicator electrode. |
| Residue on Ignition | Gravimetric Analysis | Measures inorganic ash residue after high-temperature incineration at 700-800 C and subsequent weighing. |
| pH of Aqueous Solution | pH Meter Measurement | Measures hydrogen ion activity in a 1% w/v aqueous solution using calibrated pH electrode. |
| Appearance | Visual Inspection | Assesses physical state, color, and clarity of solid material against established visual standards under controlled lighting. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range of solid-to-liquid transition using calibrated capillary apparatus per USP <741>. |
| Microbial Contamination | Membrane Filtration | Quantifies aerobic microorganisms via filtration, membrane transfer to agar media, and colony enumeration after incubation. |
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Optical Rotation | +10.0 to +12.0 deg (c=1, H2O) |
| Melting Point | 148 to 152 °C |
| Identification (NMR) | Consistent with structure |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.