China Factory Direct
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| CAS number | 114676-69-6 |
| Product name | METHYL CIS-1-BOC-4-HYDROXY-D-PROLINATE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeMaterial GradeSpecialty GradeIndustrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process Description |
|---|---|---|
| Pharmaceutical R&D | Pharmaceutical intermediates | Used as a key intermediate in the synthesis of peptides or chiral drugs to construct molecules with defined stereochemistry |
| Chemical synthesis | Organic synthesis reagent | Applied as a chiral auxiliary or catalyst in asymmetric synthesis, enabling selective protection and reaction of hydroxyl and amino groups |
| Biochemistry | Peptide and protein research | Employed in solid-phase peptide synthesis (SPPS) to introduce specific chiral structures and functional groups |
| Materials science | Chiral material preparation | Used to synthesize functional materials exhibiting chiral recognition or optical activity |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reversed-phase HPLC with UV detection at 210 nm based on peak area comparison against reference standard. |
| Chiral Purity | Chiral HPLC | Measures enantiomeric excess by separating enantiomers on a chiral stationary phase and comparing peak areas. |
| Residual Solvents | GC-FID | Detects and quantifies volatile organic solvents using gas chromatography with flame ionization detection. |
| Water Content | Karl Fischer Titration | Determines water content via coulometric or volumetric titration with iodine-based reagent reacting stoichiometrically with water. |
| Heavy Metals | ICP-MS | Quantifies trace metal impurities (e.g., Pb, Cd, Ni) by plasma ionization followed by mass spectrometric detection. |
| Residual Palladium | ICP-OES | Measures palladium residues from catalytic steps using inductively coupled plasma optical emission spectroscopy. |
| Acid Value | Acid-Base Titration | Determines free carboxylic acid content by titration with standardized NaOH solution using phenolphthalein indicator. |
| Optical Rotation | [alpha]D Measurement | Measures specific rotation using sodium D-line light to confirm chiral integrity and identity. |
| Residual BOC Reagent | GC-MS | Identifies and quantifies residual di-tert-butyl dicarbonate by gas chromatography coupled with mass spectrometry. |
| Particle Size Distribution | Laser Diffraction | Analyzes particle size distribution in suspension using Mie scattering theory applied to laser diffraction patterns. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range of solid-to-liquid transition using calibrated capillary apparatus per USP <741>. |
| Microbial Limits | Membrane Filtration | Tests for aerobic microbial count and absence of specified pathogens using membrane filtration followed by agar culture incubation. |
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Optical Rotation | +63° to +67° (c=1, in methanol) |
| Melting Point | 85°C to 89°C |
| Identification (NMR) | Conforms to reference spectrum |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.