METHYL CBZ-AMINO(DIETHOXYPHOSPHORYL)ACETATE Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 114684-69-4 |
| Product name | METHYL CBZ-AMINO(DIETHOXYPHOSPHORYL)ACETATE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for METHYL CBZ-AMINO(DIETHOXYPHOSPHORYL)ACETATE
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk METHYL CBZ-AMINO(DIETHOXYPHOSPHORYL)ACETATE Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of METHYL CBZ-AMINO(DIETHOXYPHOSPHORYL)ACETATE
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Chiral phosphonate intermediate for synthesizing protease inhibitors, antiviral agents (e.g., HIV protease inhibitors), and kinase inhibitors | Horner-Wadsworth-Emmons (HWE) condensation with aldehydes/ketones under inert atmosphere, catalyzed by base (e.g., NaH or DBU), to construct α,β-unsaturated phosphonate structures; or palladium-catalyzed cross-coupling to introduce aryl/heteroaryl groups |
| Organic Synthesis | Chiral amino acid-derived phosphonate ligand precursor for preparing chiral bidentate phosphine–palladium/rhodium catalysts | Selective methyl ester hydrolysis followed by CBZ deprotection, then cyclization with chiral diols or amino alcohols to prepare chiral bidentate phosphine ligands |
| Pesticide R&D | Structural motif in novel phosphorus-containing amino acid-based insecticides/fungicides, used to optimize lipophilicity and target binding affinity | Serves as a key building block in multistep coupling reactions (e.g., Suzuki, Stille couplings) to incorporate bioactive heterocyclic fragments, followed by oxidation/hydrolysis to modulate phosphonic acid functionality |
Manufacturing Quality Control of METHYL CBZ-AMINO(DIETHOXYPHOSPHORYL)ACETATE
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification by peak area comparison against a certified reference standard using reversed-phase chromatography and UV detection at 210-220 nm. |
| Related Substances | HPLC-UV | Separation and detection of structurally related impurities (e.g., deprotected, hydrolyzed, or isomeric forms) using gradient elution and UV monitoring. |
| Residual Solvents | GC-FID | Identification and quantification of volatile organic solvents (e.g., methanol, ethyl acetate, toluene) by gas chromatography with flame ionization detection. |
| Water Content | Karl Fischer Titration | Electrochemical titration using iodine generated in situ to determine water content based on stoichiometric reaction with Karl Fischer reagent. |
| Heavy Metals | ICP-MS | Multi-element quantification of toxic metals (e.g., Pb, Cd, Hg, As) after acid digestion, using inductively coupled plasma mass spectrometry for ultra-trace sensitivity. |
| Chloride Content | Ion Chromatography | Separation and conductivity detection of chloride ions after sample dissolution and filtration, using anion-exchange column and suppressed conductivity detection. |
| Phosphate Content | UV-Vis Spectrophotometry | Quantification of phosphate via formation of phosphomolybdate complex under acidic conditions and measurement of absorbance at 880 nm. |
| Optical Rotation | [alpha]D Measurement | Determination of specific optical rotation using a polarimeter at 20 C and sodium D-line (589 nm) to confirm chiral integrity and enantiomeric purity. |
| Residual Catalyst (Pd) | ICP-OES | Quantification of palladium residues after microwave-assisted acid digestion using inductively coupled plasma optical emission spectroscopy. |
| Acid Value | Acid-Base Titration | Neutralization of free carboxylic acid groups with standardized NaOH solution using phenolphthalein indicator or potentiometric endpoint detection. |
| Appearance | Visual Inspection | Assessment of physical state, color, and clarity of the solid material against established reference standards under controlled lighting conditions. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry powder particle size distribution by measuring angular dependence of laser light scattering intensity. |
Technical Specifications of METHYL CBZ-AMINO(DIETHOXYPHOSPHORYL)ACETATE
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow solid |
| Purity | >=98.0% (by LC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 85–89°C |
| Identification (NMR) | Conforms to reference spectrum |
| Optical Rotation | +12.0° to +16.0° (c=1, CHCl3) |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of METHYL CBZ-AMINO(DIETHOXYPHOSPHORYL)ACETATE
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of METHYL CBZ-AMINO(DIETHOXYPHOSPHORYL)ACETATE
Safety Information of METHYL CBZ-AMINO(DIETHOXYPHOSPHORYL)ACETATE
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of METHYL CBZ-AMINO(DIETHOXYPHOSPHORYL)ACETATE
Industrial METHYL CBZ-AMINO(DIETHOXYPHOSPHORYL)ACETATE Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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