(S)-(+)-1-Benzyl-3-aminopyrrolidine Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 114715-38-7 |
| Product name | (S)-(+)-1-Benzyl-3-aminopyrrolidine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25L/drum |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for (S)-(+)-1-Benzyl-3-aminopyrrolidine
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk (S)-(+)-1-Benzyl-3-aminopyrrolidine Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of (S)-(+)-1-Benzyl-3-aminopyrrolidine
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Chiral intermediates for synthesis of antiviral agents (e.g., HCV NS3/4A protease inhibitors) | Chiral resolution or asymmetric synthesis to install key chiral centers |
| Pharmaceuticals | Construction of nitrogen-containing heterocyclic structures in drug candidates | Used as chiral amines in reductive amination, Buchwald–Hartwig coupling, and other coupling reactions |
| Fine Chemicals | Precursors for chiral catalyst ligands | Derivatized to prepare chiral phosphine–amine or N,N-bidentate ligands for asymmetric hydrogenation and related reactions |
Manufacturing Quality Control of (S)-(+)-1-Benzyl-3-aminopyrrolidine
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reversed-phase HPLC with UV detection at 210-230 nm, comparing peak area to a certified reference standard. |
| Enantiomeric Excess (ee) | Chiral HPLC | Separates (S)- and (R)-enantiomers on a chiral stationary phase; ee calculated from peak area ratio of enantiomers. |
| Water Content | Karl Fischer Titration | Measures water via coulometric or volumetric titration using iodine-based reagent reacting stoichiometrically with water. |
| Residual Solvents | GC-FID | Quantifies volatile organic solvents (e.g., methanol, ethyl acetate) by gas chromatography with flame ionization detection. |
| Heavy Metals | ICP-MS | Detects trace metal impurities (e.g., Pd, Ni, Fe) after acid digestion using inductively coupled plasma mass spectrometry. |
| Chloride Content | Ion Chromatography | Separates and quantifies chloride ions using anion-exchange column and conductivity detection. |
| Sulfated Ash | Gravimetric Analysis | Measures inorganic residue after high-temperature combustion in presence of sulfuric acid, followed by weighing. |
| Optical Rotation | [alpha]D Measurement | Determines specific optical rotation using sodium D-line light source to confirm chiral integrity and concentration. |
| Related Substances | HPLC-UV (Gradient) | Detects and quantifies structurally related impurities (e.g., de-benzylated, oxidized, or dimeric species) using gradient elution. |
| pH (1% w/v aqueous solution) | pH Meter | Measures hydrogen ion activity in aqueous solution using calibrated glass electrode system. |
| Appearance | Visual Inspection | Assesses physical state, color, and clarity against standard references under controlled lighting conditions. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range at which solid transitions to liquid using calibrated capillary method per USP <741>. |
Technical Specifications of (S)-(+)-1-Benzyl-3-aminopyrrolidine
| Test Item | Specification |
|---|---|
| Appearance | Yellow liquid |
| Purity | >=98.0% (HPLC) |
| Optical Rotation | +9.3 to +9.7 (c=1, in methanol) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Odor | Characteristic odor |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of (S)-(+)-1-Benzyl-3-aminopyrrolidine
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of (S)-(+)-1-Benzyl-3-aminopyrrolidine
Safety Information of (S)-(+)-1-Benzyl-3-aminopyrrolidine
| Pictograms |  |
| Signal Word | Danger |
| Safety Data Sheet | |
Packaging of (S)-(+)-1-Benzyl-3-aminopyrrolidine
Industrial (S)-(+)-1-Benzyl-3-aminopyrrolidine Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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