China Factory Direct
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| CAS number | 114772-34-8 |
| Product name | 4′-Methylbiphenyl-2-carboxylic acid methyl ester |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Key intermediate in the synthesis of antihypertensive drugs—specifically angiotensin II receptor blockers (ARBs)—such as telmisartan | Converted into the target active pharmaceutical ingredient (API) via multistep organic synthesis, including nucleophilic substitution, hydrolysis, and amidation |
| Pesticides | Structural intermediate for certain herbicides or plant growth regulators | Used to construct the pesticide molecular scaffold through aromatic ring functional group transformation, transesterification, or coupling reactions |
| Fine Chemicals | Precursor for liquid crystal materials or organic functional materials | Specific substituents are introduced to tune optoelectronic properties via Suzuki coupling, ester group transformation, or metal-catalyzed cross-coupling reactions |
| Test Item | Common Testing Method | Method Summary |
|---|---|---|
| Identification Test | Infrared Spectroscopy (IR) | Determine the infrared absorption spectrum of the sample and compare it with the reference spectrum to confirm consistency of characteristic functional group absorption peaks (such as ester C=O, aromatic ring C–H, etc.) of 4'-methylbiphenyl-2-carboxylic acid methyl ester. |
| Proton Nuclear Magnetic Resonance (¹H NMR) | Use NMR technology to analyze chemical shifts, integration areas, and coupling constants of hydrogen atoms in the compound to verify whether the molecular structure matches the target compound. | |
| Assay | High-Performance Liquid Chromatography (HPLC) | Employ a reversed-phase C18 column with methanol-water or acetonitrile-water as the mobile phase, and use a UV detector (typically around 254 nm). The content of the main component is determined by external standard or internal standard method. |
| Related Substances / Impurity Testing | High-Performance Liquid Chromatography (HPLC) | Use chromatographic conditions similar to those for assay, but optimize the gradient elution program to achieve good separation between the main peak and potential impurities (e.g., starting materials, intermediates, degradation products). Impurity levels are calculated using the area normalization method or the main component self-dilution method with correction factors. |
| Residual Solvents | Gas Chromatography (GC) | Use headspace or direct injection, along with polar or nonpolar capillary columns and an FID detector. Perform qualitative and quantitative analysis of organic solvents potentially remaining from synthesis (e.g., methanol, toluene, dichloromethane) according to pharmacopoeial or ICH guidelines. |
| Loss on Drying | Thermogravimetric Analysis (TGA) or Constant Temperature Atmospheric Drying Method | Dry the sample at a specified temperature (e.g., 105°C) until constant weight is achieved, and determine the percentage of mass loss to evaluate moisture and volatile matter content. |
| Melting Point | Capillary Melting Point Determination | Use a melting point apparatus to measure the temperature range from initial melting to complete melting, serving as an auxiliary indicator for purity and identity confirmation. |
| Heavy Metals | Atomic Absorption Spectroscopy (AAS) or Inductively Coupled Plasma Mass Spectrometry (ICP-MS) | After digestion of the sample, determine residual levels of harmful elements such as lead, cadmium, mercury, and arsenic to ensure compliance with pharmaceutical or industrial safety standards. |
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 78–82°C |
| Identification (NMR) | Conforms to reference spectrum |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.