Methyl 4'-bromomethyl biphenyl-2-carboxylate Bulk Supply for Industrial Use
China Factory Direct
 |
|
| CAS number | 114772-38-2 |
| Product name | Methyl 4'-bromomethyl biphenyl-2-carboxylate |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Material GradeSpecialty GradeIndustrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
QUOTE TYPE
PACKAGING TYPE
TOTAL QUANTITY(KG)
PREFERRED SHIPPING METHOD
YOUR COMPANY
YOUR E-MAIL
Calculate Summary
Based on current marketvolatility and material availability.
Documents We Provide for Methyl 4'-bromomethyl biphenyl-2-carboxylate
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk Methyl 4'-bromomethyl biphenyl-2-carboxylate Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of Methyl 4'-bromomethyl biphenyl-2-carboxylate
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Key intermediate for synthesizing angiotensin II receptor blockers (e.g., losartan, valsartan) | Undergoes nucleophilic substitution with imidazole derivatives under basic conditions to construct the biphenyl tetrazole structure |
| Organic Synthesis | Multifunctional biphenyl derivative used to build heterocycle–biphenyl frameworks containing bromomethyl and ester groups | Participates in Williamson ether synthesis via the bromomethyl group; undergoes ester hydrolysis/ammonolysis; or serves as a substrate in palladium-catalyzed cross-coupling reactions (e.g., Heck, Suzuki) |
| Materials Science | Structural unit for liquid crystal monomers or organic electroluminescent (OLED) materials | After hydrolysis to the corresponding carboxylic acid, undergoes condensation with alcohols or amines; alternatively, the bromomethyl group is converted to other functional groups to tune molecular polarity and conjugation length |
Manufacturing Quality Control of Methyl 4'-bromomethyl biphenyl-2-carboxylate
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination based on peak area comparison against a certified reference standard using reversed-phase chromatography and UV detection at ~254 nm. |
| Related Substances | HPLC-UV/DAD | Separation and identification of impurities (e.g., starting materials, isomers, dehalogenated by-products) via gradient HPLC with diode-array detection and threshold-based reporting per ICH Q3A/B. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify common solvents (e.g., methanol, toluene, DMF) against calibrated standards per ICH Q3C. |
| Water Content | Karl Fischer Titration (Coulometric) | Electrochemical titration measuring water via iodine generation and stoichiometric reaction with water in anhydrous medium. |
| Heavy Metals | ICP-MS | Multi-element quantification of toxic elements (e.g., Pb, Cd, Hg, Ni) after acid digestion, using isotopic detection with sub-ppt sensitivity. |
| Chloride Impurity | Ion Chromatography (IC) | Separation and conductivity detection of chloride ions released from hydrolyzable impurities or residual reagents. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition measurement using controlled heating rate; used for identity confirmation and purity screening per USP <741>. |
| Residue on Ignition | Gravimetric Analysis (Sulfated Ash) | Mass difference after high-temperature incineration (700–800 °C) to determine inorganic residue content per USP <281>. |
Technical Specifications of Methyl 4'-bromomethyl biphenyl-2-carboxylate
| Test Item | Specification |
|---|---|
| Appearance | Orange solid |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 118–122°C |
| Identification (NMR) | Conforms to reference spectrum |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
|
|
Download COA of Methyl 4'-bromomethyl biphenyl-2-carboxylate
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of Methyl 4'-bromomethyl biphenyl-2-carboxylate
Safety Information of Methyl 4'-bromomethyl biphenyl-2-carboxylate
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of Methyl 4'-bromomethyl biphenyl-2-carboxylate
Industrial Methyl 4'-bromomethyl biphenyl-2-carboxylate Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
Use Bulk
Supply Factory
Direct ISO 9001
Certified Samples
Available Stable
Supply